| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPM1B | DYRK1A | Ser258 | NTNFRGVsLNLTRKF | dephosphorylation down-regulates activity | 33380426 | SIGNOR-277108 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPM1B | dephosphorylation down-regulates ⊣ | DYRK1A PSer258 | dephosphorylation up-regulates → | DYRK1A | 33380426 | SIGNOR-277108 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPM1B | dephosphorylation → down-regulates activity | DYRK1A | SIGNOR-277108 |
