| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DYRK1A | DYRK1A | Tyr321 | LGQRIYQyIQSRFYR | phosphorylation up-regulates activity | 11672423 | SIGNOR-111145 |
| DYRK1A | DYRK1A | Tyr321 | LGQRIYQyIQSRFYR | phosphorylation up-regulates | 10910078 | SIGNOR-79764 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DYRK1A | phosphorylation up-regulates → | DYRK1A PTyr321 | phosphorylation up-regulates → | DYRK1A | 11672423 | SIGNOR-111145 |
| DYRK1A | phosphorylation up-regulates → | DYRK1A PTyr321 | phosphorylation up-regulates → | DYRK1A | 10910078 | SIGNOR-79764 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| DYRK1A | phosphorylation → up-regulates activity | DYRK1A | SIGNOR-111145 |
| DYRK1A | phosphorylation → up-regulates | DYRK1A | SIGNOR-79764 |
