Entity Details

Name ABL1_Tyr486
ID Q14247
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTK2CTTNTyr486YPAEDSTyDEYENDLphosphorylation
down-regulates activity		22952866SIGNOR-278285
PTK2BCTTNTyr486YPAEDSTyDEYENDLphosphorylation
up-regulates activity		29133485SIGNOR-278345
ABL1CTTNTyr486YPAEDSTyDEYENDLphosphorylation
up-regulates activity		20861316SIGNOR-278504
SRCCTTNTyr486YPAEDSTyDEYENDLphosphorylation
down-regulates		12601080SIGNOR-98720
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PTK2phosphorylation
up-regulates
→
CTTN
PTyr486		phosphorylation
down-regulates
⊣		CTTN22952866SIGNOR-278285
PTK2Bphosphorylation
up-regulates
→
CTTN
PTyr486		phosphorylation
up-regulates
→		CTTN29133485SIGNOR-278345
ABL1phosphorylation
up-regulates
→
CTTN
PTyr486		phosphorylation
up-regulates
→		CTTN20861316SIGNOR-278504
SRCphosphorylation
up-regulates
→
CTTN
PTyr486		phosphorylation
down-regulates
⊣		CTTN12601080SIGNOR-98720
Regulator Mechanism/Effect Target SIGNOR-ID
PTK2phosphorylation
→
down-regulates activity 		CTTNSIGNOR-278285
PTK2Bphosphorylation
→
up-regulates activity 		CTTNSIGNOR-278345
ABL1phosphorylation
→
up-regulates activity 		CTTNSIGNOR-278504
SRCphosphorylation
img/direct_inhibition.png
down-regulates 		CTTNSIGNOR-98720