| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCD | CTTN | Ser405 | KTQTPPVsPAPQPTE | phosphorylation up-regulates activity | 26490115 | SIGNOR-260889 |
| MAPK1 | CTTN | Ser405 | KTQTPPVsPAPQPTE | phosphorylation up-regulates | 20444238 | SIGNOR-165200 |
| MAPK3 | CTTN | Ser405 | KTQTPPVsPAPQPTE | phosphorylation up-regulates | 20444238 | SIGNOR-165208 |
| MAPK3 | CTTN | Ser405 | KTQTPPVsPAPQPTE | phosphorylation up-regulates | 21079800 | SIGNOR-169682 |
| PAK1 | CTTN | Ser405 | KTQTPPVsPAPQPTE | phosphorylation up-regulates | 20444238 | SIGNOR-165216 |
| MAPK1 | CTTN | Ser405 | KTQTPPVsPAPQPTE | phosphorylation up-regulates | 21079800 | SIGNOR-169674 |
| PAK1 | CTTN | Ser405 | KTQTPPVsPAPQPTE | phosphorylation up-regulates | 21079800 | SIGNOR-169690 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCD | phosphorylation up-regulates → | CTTN PSer405 | phosphorylation up-regulates → | CTTN | 26490115 | SIGNOR-260889 |
| MAPK1 | phosphorylation up-regulates → | CTTN PSer405 | phosphorylation up-regulates → | CTTN | 20444238 | SIGNOR-165200 |
| MAPK3 | phosphorylation up-regulates → | CTTN PSer405 | phosphorylation up-regulates → | CTTN | 20444238 | SIGNOR-165208 |
| MAPK3 | phosphorylation up-regulates → | CTTN PSer405 | phosphorylation up-regulates → | CTTN | 21079800 | SIGNOR-169682 |
| PAK1 | phosphorylation up-regulates → | CTTN PSer405 | phosphorylation up-regulates → | CTTN | 20444238 | SIGNOR-165216 |
| MAPK1 | phosphorylation up-regulates → | CTTN PSer405 | phosphorylation up-regulates → | CTTN | 21079800 | SIGNOR-169674 |
| PAK1 | phosphorylation up-regulates → | CTTN PSer405 | phosphorylation up-regulates → | CTTN | 21079800 | SIGNOR-169690 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCD | phosphorylation → up-regulates activity | CTTN | SIGNOR-260889 |
| MAPK1 | phosphorylation → up-regulates | CTTN | SIGNOR-165200 |
| MAPK3 | phosphorylation → up-regulates | CTTN | SIGNOR-165208 |
| MAPK3 | phosphorylation → up-regulates | CTTN | SIGNOR-169682 |
| PAK1 | phosphorylation → up-regulates | CTTN | SIGNOR-165216 |
| MAPK1 | phosphorylation → up-regulates | CTTN | SIGNOR-169674 |
| PAK1 | phosphorylation → up-regulates | CTTN | SIGNOR-169690 |
