| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | CTTN | Tyr470 | AYATEAVyESAEAPG | phosphorylation down-regulates | 12601080 | SIGNOR-98716 |
| PTK2 | CTTN | Tyr470 | AYATEAVyESAEAPG | phosphorylation down-regulates activity | 22952866 | SIGNOR-278283 |
| PTPRG | CTTN | Tyr470 | AYATEAVyESAEAPG | dephosphorylation down-regulates activity | 25624455 | SIGNOR-254696 |
| PTK2B | CTTN | Tyr470 | AYATEAVyESAEAPG | phosphorylation up-regulates activity | 29133485 | SIGNOR-278344 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | CTTN PTyr470 | phosphorylation down-regulates ⊣ | CTTN | 12601080 | SIGNOR-98716 |
| PTK2 | phosphorylation up-regulates → | CTTN PTyr470 | phosphorylation down-regulates ⊣ | CTTN | 22952866 | SIGNOR-278283 |
| PTPRG | dephosphorylation down-regulates ⊣ | CTTN PTyr470 | dephosphorylation up-regulates → | CTTN | 25624455 | SIGNOR-254696 |
| PTK2B | phosphorylation up-regulates → | CTTN PTyr470 | phosphorylation up-regulates → | CTTN | 29133485 | SIGNOR-278344 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation down-regulates | CTTN | SIGNOR-98716 |
| PTK2 | phosphorylation → down-regulates activity | CTTN | SIGNOR-278283 |
| PTPRG | dephosphorylation → down-regulates activity | CTTN | SIGNOR-254696 |
| PTK2B | phosphorylation → up-regulates activity | CTTN | SIGNOR-278344 |
