| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATM | SMC1A | Ser966 | GEDSVSGsQRISSIY | phosphorylation up-regulates | 11877377 | SIGNOR-115496 |
| ATM | SMC1A | Ser966 | GEDSVSGsQRISSIY | phosphorylation up-regulates activity | 11877376 | SIGNOR-255589 |
| ATM | SMC1A | Ser957 | ISQEEGSsQGEDSVS | phosphorylation up-regulates | 11877377 | SIGNOR-115492 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATM | phosphorylation up-regulates → | SMC1A PSer966 | phosphorylation up-regulates → | SMC1A | 11877377 | SIGNOR-115496 |
| ATM | phosphorylation up-regulates → | SMC1A PSer966 | phosphorylation up-regulates → | SMC1A | 11877376 | SIGNOR-255589 |
| ATM | phosphorylation up-regulates → | SMC1A PSer957 | phosphorylation up-regulates → | SMC1A | 11877377 | SIGNOR-115492 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ATM | phosphorylation → up-regulates | SMC1A | SIGNOR-115496 |
| ATM | phosphorylation → up-regulates activity | SMC1A | SIGNOR-255589 |
| ATM | phosphorylation → up-regulates | SMC1A | SIGNOR-115492 |
