Entity Details

Name LPIN1
ID Q14693
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCLPIN1Tyr398HLGADGVyLDDLTDMphosphorylation
up-regulates activity		33203880SIGNOR-277292
CTDNEP1LPIN1Ser106
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IPMHLATsPILSEGAdephosphorylation
up-regulates activity		17420445SIGNOR-248346
CHKALPIN1–phosphorylation
down-regulates activity		28049764SIGNOR-280228
SRCLPIN1Tyr795FPNTEPFyAAFGNRPphosphorylation
up-regulates activity		33203880SIGNOR-277291
SRCLPIN1Tyr413DPEVAALyFPKNGDPphosphorylation
up-regulates activity		33203880SIGNOR-277293
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
LPIN1
PTyr398		phosphorylation
up-regulates
→		LPIN133203880SIGNOR-277292
CTDNEP1dephosphorylation
down-regulates
⊣
LPIN1
PSer106		dephosphorylation
down-regulates
⊣		LPIN117420445SIGNOR-248346
SRCphosphorylation
up-regulates
→
LPIN1
PTyr795		phosphorylation
up-regulates
→		LPIN133203880SIGNOR-277291
SRCphosphorylation
up-regulates
→
LPIN1
PTyr413		phosphorylation
up-regulates
→		LPIN133203880SIGNOR-277293
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
up-regulates activity 		LPIN1SIGNOR-277292
CTDNEP1dephosphorylation
→
up-regulates activity 		LPIN1SIGNOR-248346
CHKAphosphorylation
→
down-regulates activity 		LPIN1SIGNOR-280228
SRCphosphorylation
→
up-regulates activity 		LPIN1SIGNOR-277291
SRCphosphorylation
→
up-regulates activity 		LPIN1SIGNOR-277293