| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LATS1 | MTF1 | Ser152 | EGCPRTYsTAGNLRT | phosphorylation down-regulates activity | 35027733 | SIGNOR-275473 |
| LATS2 | MTF1 | Ser152 | EGCPRTYsTAGNLRT | phosphorylation down-regulates activity | 35027733 | SIGNOR-275475 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LATS1 | phosphorylation up-regulates → | MTF1 PSer152 | phosphorylation down-regulates ⊣ | MTF1 | 35027733 | SIGNOR-275473 |
| LATS2 | phosphorylation up-regulates → | MTF1 PSer152 | phosphorylation down-regulates ⊣ | MTF1 | 35027733 | SIGNOR-275475 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| LATS1 | phosphorylation → down-regulates activity | MTF1 | SIGNOR-275473 |
| LATS2 | phosphorylation → down-regulates activity | MTF1 | SIGNOR-275475 |