Entity Details

Name AKT1_Thr346
ID Q15118
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT2PDK1Thr346APRPRVEtSRAVPLAphosphorylation
up-regulates activity		27505672SIGNOR-277271
AKT1PDK1Thr346APRPRVEtSRAVPLAphosphorylation
up-regulates activity		27505672SIGNOR-277272
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT2phosphorylation
up-regulates
→
PDK1
PThr346		phosphorylation
up-regulates
→		PDK127505672SIGNOR-277271
AKT1phosphorylation
up-regulates
→
PDK1
PThr346		phosphorylation
up-regulates
→		PDK127505672SIGNOR-277272
Regulator Mechanism/Effect Target SIGNOR-ID
AKT2phosphorylation
→
up-regulates activity 		PDK1SIGNOR-277271
AKT1phosphorylation
→
up-regulates activity 		PDK1SIGNOR-277272