Entity Details

Name PDK1_Thr346
ID Q15118
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT2PDK1Thr346APRPRVEtSRAVPLAphosphorylation
up-regulates activity		27505672SIGNOR-277271
AKT1PDK1Thr346APRPRVEtSRAVPLAphosphorylation
up-regulates activity		27505672SIGNOR-277272
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT2phosphorylation
up-regulates
→
PDK1
PThr346		phosphorylation
up-regulates
→		PDK127505672SIGNOR-277271
AKT1phosphorylation
up-regulates
→
PDK1
PThr346		phosphorylation
up-regulates
→		PDK127505672SIGNOR-277272
Regulator Mechanism/Effect Target SIGNOR-ID
AKT2phosphorylation
→
up-regulates activity 		PDK1SIGNOR-277271
AKT1phosphorylation
→
up-regulates activity 		PDK1SIGNOR-277272