Entity Details

Name AKT1_Ser21
ID Q15910
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT1EZH2Ser21CWRKRVKsEYMRLRQphosphorylation
down-regulates activity		16224021SIGNOR-141043
AKTEZH2Ser21CWRKRVKsEYMRLRQphosphorylation
down-regulates activity		16224021SIGNOR-244259
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT1phosphorylation
up-regulates
→
EZH2
PSer21		phosphorylation
down-regulates
⊣		EZH216224021SIGNOR-141043
AKTphosphorylation
up-regulates
→
EZH2
PSer21		phosphorylation
down-regulates
⊣		EZH216224021SIGNOR-244259
Regulator Mechanism/Effect Target SIGNOR-ID
AKT1phosphorylation
→
down-regulates activity 		EZH2SIGNOR-141043
AKTphosphorylation
→
down-regulates activity 		EZH2SIGNOR-244259