| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATM | EZH2 | Ser729 | LFFDYRYsQADALKY | phosphorylation down-regulates quantity by destabilization | 24162653 | SIGNOR-276602 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATM | phosphorylation up-regulates → | EZH2 PSer729 | phosphorylation down-regulates ⊣ | EZH2 | 24162653 | SIGNOR-276602 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ATM | phosphorylation down-regulates quantity by destabilization | EZH2 | SIGNOR-276602 |
