| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATM | EZH2 | Ser734 | S-->L | phosphorylation down-regulates quantity | 24162653 | SIGNOR-279586 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATM | phosphorylation up-regulates → | EZH2 PSer734 | phosphorylation down-regulates ⊣ | EZH2 | 24162653 | SIGNOR-279586 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ATM | phosphorylation → down-regulates quantity | EZH2 | SIGNOR-279586 |
