| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | EZH2 | Thr345 | LTAERIKtPPKRPGG | phosphorylation down-regulates | 21659531 | SIGNOR-174054 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | phosphorylation up-regulates → | EZH2 PThr345 | phosphorylation down-regulates ⊣ | EZH2 | 21659531 | SIGNOR-174054 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK1 | phosphorylation down-regulates | EZH2 | SIGNOR-174054 |
