Entity Details

Name GSK3B_Thr367
ID Q15910
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GSK3BEZH2Thr367NNSSRPStPTINVLEphosphorylation
down-regulates activity		27494834SIGNOR-278175
MAPK14EZH2Thr367NNSSRPStPTINVLEphosphorylation
down-regulates quantity by destabilization		28067271SIGNOR-255663
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GSK3Bphosphorylation
up-regulates
→
EZH2
PThr367		phosphorylation
down-regulates
⊣		EZH227494834SIGNOR-278175
MAPK14phosphorylation
up-regulates
→
EZH2
PThr367		phosphorylation
down-regulates
⊣		EZH228067271SIGNOR-255663
Regulator Mechanism/Effect Target SIGNOR-ID
GSK3Bphosphorylation
→
down-regulates activity 		EZH2SIGNOR-278175
MAPK14phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		EZH2SIGNOR-255663