| Name | MAPK14 |
| ID | Q16539 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 24-308 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK14 | FOXC1 | Ser272 | SSLSSGSsPPGSLPS | phosphorylation up-regulates quantity by stabilization | 31650548 | SIGNOR-275911 |
| MAPK14 | GLI1 | Ser937 | FLGGSQVsPSRAKAP | phosphorylation down-regulates quantity by destabilization | 38307877 | SIGNOR-277916 |
| MAPK14 | GSK3B | Ser389 | ARIQAAAsTPTNATA | phosphorylation down-regulates | 17726008 | SIGNOR-157548 |
| MAPK14 | MAPT | – | phosphorylation up-regulates | 20626350 | SIGNOR-166611 | |
| MAPK14 | NCOA3 | Ser505 | SPVAGVHsPMASSGN | phosphorylation up-regulates activity | 15383283 | SIGNOR-250103 |
| MAPK14 | ATF6 | Thr166 | NKTENGLtPKKKIQV | phosphorylation up-regulates activity | 25135476 | SIGNOR-276841 |
| MAPK14 | ELAVL1 | Thr118 | SGLPRTMtQKDVEDM | phosphorylation up-regulates | 19528229 | SIGNOR-186135 |
| MAPK14 | RB1 | Ser567 | SLAWLSDsPLFDLIK | phosphorylation down-regulates | 20871633 | SIGNOR-168178 |
| MAPK14 | NCOA3 | Ser543 | SLLSTLSsPGPKLDN | phosphorylation up-regulates activity | 15383283 | SIGNOR-250104 |
| MAPK14 | ATF2 | – | phosphorylation up-regulates activity | 10085140 | SIGNOR-65593 | |
| MAPK14 | H3C1 | Ser11 | TKQTARKsTGGKAPR | phosphorylation unknown | 20626350 | SIGNOR-166602 |
| MAPK14 | TP53 | Ser33 | LPENNVLsPLPSQAM | phosphorylation up-regulates | 17535811 | SIGNOR-155242 |
| MAPK14 | SMAD3 | – | phosphorylation up-regulates activity | 14512875 | SIGNOR-236136 | |
| MAPK14 | PTPN7 | Ser93 | ALQRQPPsPKQLEEE | phosphorylation down-regulates activity | 10206983 | SIGNOR-250109 |
| MAPK14 | MEF2A | Ser408 | SIKSEPIsPPRDRMT | phosphorylation unknown | 12586839 | SIGNOR-98224 |
| MAPK14 | TP53 | Ser46 | AMDDLMLsPDDIEQW | phosphorylation up-regulates activity | 17535811 | SIGNOR-155246 |
| MAPK14 | NFATC1 | Ser172 | YRDPSCLsPASSLSS | phosphorylation down-regulates | 10652349 | SIGNOR-74560 |
| MAPK14 | FOXO | Ser7 | sPAPLSPL | phosphorylation up-regulates | 22128155 | SIGNOR-252960 |
| MAPK14 | SMAD3 | Ser208 | DAGSPNLsPNPMSPA | phosphorylation up-regulates activity | 15520018 | SIGNOR-250112 |
| MAPK14 | CDX2 | Ser295 | LQASVPGsVPGVLGP | phosphorylation down-regulates quantity by destabilization | 16027724 | SIGNOR-250095 |
| MAPK14 | ELK1 | Ser383 | IHFWSTLsPIAPRSP | phosphorylation up-regulates | 9130707 | SIGNOR-47630 |
| MAPK14 | USF1 | Thr153 | EALLGQAtPPGTGQF | phosphorylation up-regulates activity | 19389701 | SIGNOR-185572 |
| MAPK14 | JUNB | Ser79 | QGSDTGAsLKLASSE | phosphorylation up-regulates | 15308641 | SIGNOR-127545 |
| MAPK14 | TP53 | Ser33 | LPENNVLsPLPSQAM | phosphorylation up-regulates | 11258706 | SIGNOR-105741 |
| MAPK14 | SLC9A1 | Ser729 | ASPQSPEsVDLVNEE | phosphorylation up-regulates | 18701649 | SIGNOR-180048 |
| MAPK14 | ELK1 | Ser389 | LSPIAPRsPAKLSFQ | phosphorylation up-regulates | 9130707 | SIGNOR-47634 |
| MAPK14 | ZNHIT1 | – | phosphorylation up-regulates | 20473270 | SIGNOR-165571 | |
| MAPK14 | PIAS2 | Ser116 | VTPHSPSsPVGSVLL | phosphorylation up-regulates activity | 16713578 | SIGNOR-262949 |
| MAPK14 | MAPKAPK2 | Thr222 | TSHNSLTtPCYTPYY | phosphorylation up-regulates activity | 14499342 | SIGNOR-118040 |
| MAPK14 | MEF2A | Thr319 | TPVVSVTtPSLPPQG | phosphorylation up-regulates | 9858528 | SIGNOR-62784 |
| MAPK14 | NR3C1 | Ser211 | PGKETNEsPWRSDLL | phosphorylation up-regulates | 20660302 | SIGNOR-255952 |
| MAPK14 | MEF2A | Ser453 | PRQEMGRsPVDSLSS | phosphorylation unknown | 12586839 | SIGNOR-98228 |
| MAPK14 | SP7 | – | phosphorylation up-regulates activity | 20682789 | SIGNOR-255791 | |
| MAPK14 | EWSR1 | Thr79 | QPPTGYTtPTAPQAY | phosphorylation unknown | 19076070 | SIGNOR-182778 |
| MAPK14 | ESR1 | Ser118 | LHPPPQLsPFLQPHG | phosphorylation up-regulates | 15879307 | SIGNOR-136950 |
| MAPK14 | GATA2 | – | phosphorylation up-regulates | 25056917 | SIGNOR-205242 | |
| MAPK14 | STAT3 | Ser727 | NTIDLPMsPRTLDSL | phosphorylation up-regulates | 18691976 | SIGNOR-179912 |
| MAPK14 | H3-3A | – | phosphorylation unknown | 10806218 | SIGNOR-77224 | |
| MAPK14 | NCOA3 | Ser860 | NRAVSLDsPVSVGSS | phosphorylation up-regulates activity | 15383283 | SIGNOR-250105 |
| MAPK14 | TP53 | Ser46 | AMDDLMLsPDDIEQW | phosphorylation up-regulates activity | 15642743 | SIGNOR-226620 |
| MAPK14 | TCF3 | Ser139 | LNSPGPLsPSGMKGT | phosphorylation up-regulates activity | 15719023 | SIGNOR-134194 |
| MAPK14 | SMAD3 | Ser204 | NHSMDAGsPNLSPNP | phosphorylation up-regulates activity | 15520018 | SIGNOR-250113 |
| MAPK14 | MEF2C | Thr293 | QSAQSLAtPVVSVAT | phosphorylation up-regulates activity | 9858528 | SIGNOR-62792 |
| MAPK14 | RUNX2 | – | phosphorylation up-regulates activity | 20551513 | SIGNOR-255777 | |
| MAPK14 | FGFR1 | Ser777 | SMPLDQYsPSFPDTR | phosphorylation down-regulates | 20626350 | SIGNOR-166598 |
| MAPK14 | CDX2 | Ser291 | PVSSLQAsVPGSVPG | phosphorylation down-regulates quantity by destabilization | 16027724 | SIGNOR-250094 |
| MAPK14 | STAT1 | Ser727 | TDNLLPMsPEEFDEV | phosphorylation up-regulates activity | 17502367 | SIGNOR-154779 |
| MAPK14 | KAT5 | Thr158 | VEVVSPAtPVPSETA | phosphorylation up-regulates activity | 25544752 | SIGNOR-278958 |
| MAPK14 | CDKN1C | – | phosphorylation up-regulates | 22820251 | SIGNOR-198390 | |
| MAPK14 | RBPJ | Thr339 | STDKAEYtFYEGMGP | phosphorylation down-regulates quantity by destabilization | 22302987 | SIGNOR-276403 |
| MAPK14 | DDIT3 | Ser79 | EVTSTSQsPHSPDSS | phosphorylation up-regulates activity | 8650547 | SIGNOR-42200 |
| MAPK14 | AKT2 | Ser474 | RTHFPQFsYSASIRE | phosphorylation up-regulates activity | 12181443 | SIGNOR-91408 |
| MAPK14 | DLX5 | Ser34 | MHHPSQEsPTLPESS | phosphorylation up-regulates activity | 18056716 | SIGNOR-255792 |
| MAPK14 | CCND1 | – | phosphorylation up-regulates | 20626350 | SIGNOR-166594 | |
| MAPK14 | CDX2 | Ser287 | EPLSPVSsLQASVPG | phosphorylation down-regulates quantity by destabilization | 16027724 | SIGNOR-250093 |
| MAPK14 | MAPKAPK2 | Thr317 | PTQRMTItEFMNHPW | phosphorylation up-regulates activity | 7592979 | SIGNOR-250102 |
| MAPK14 | RPS6KA4 | Ser347 | PVYSPPGsPPPGDPR | phosphorylation up-regulates | 10806207 | SIGNOR-77212 |
| MAPK14 | PLA2G4A | Ser505 | LNTSYPLsPLSDFAT | phosphorylation up-regulates activity | 8910365 | SIGNOR-44673 |
| MAPK14 | PPARGC1A | Thr263 | TTLSLPLtPESPNDP | phosphorylation up-regulates | 11741533 | SIGNOR-112770 |
| MAPK14 | TAB1 | Ser438 | TPTLTNQsPTLTLQS | phosphorylation down-regulates activity | 14592977 | SIGNOR-118922 |
| MAPK14 | EZH2 | Thr367 | NNSSRPStPTINVLE | phosphorylation down-regulates quantity by destabilization | 28067271 | SIGNOR-255663 |
| MAPK14 | PIAS2 | Ser113 | STSVTPHsPSSPVGS | phosphorylation up-regulates activity | 16713578 | SIGNOR-262948 |
| MAPK14 | FOXC1 | Ser241 | PSPPQPLsPAAALGS | phosphorylation up-regulates quantity by stabilization | 31650548 | SIGNOR-275913 |
| MAPK14 | GLI1 | Ser982 | VVGANRAsHRAAAPP | phosphorylation down-regulates quantity by destabilization | 38307877 | SIGNOR-277917 |
| MAPK14 | RPS6KA5 | Thr581 | PDNQPLKtPCFTLHY | phosphorylation up-regulates activity | 15568999 | SIGNOR-131375 |
| MAPK14 | ATF2 | Thr71 | IVADQTPtPTRFLKN | phosphorylation up-regulates | 10085140 | SIGNOR-65601 |
| MAPK14 | RPS6KA4 | Ser360 | PRIFQGYsFVAPSIL | phosphorylation up-regulates | 10806207 | SIGNOR-77216 |
| MAPK14 | SLC9A1 | Ser726 | IDPASPQsPESVDLV | phosphorylation up-regulates | 18701649 | SIGNOR-180044 |
| MAPK14 | MAP3K11 | – | phosphorylation down-regulates | 20626350 | SIGNOR-166605 | |
| MAPK14 | ATF2 | Thr71 | IVADQTPtPTRFLKN | phosphorylation up-regulates | 12110590 | SIGNOR-90525 |
| MAPK14 | RPS6KA4 | Thr568 | SPGVPMQtPCFTLQY | phosphorylation up-regulates | 10806207 | SIGNOR-77220 |
| MAPK14 | MEF2D | – | phosphorylation up-regulates activity | 18026121 | SIGNOR-159331 | |
| MAPK14 | MAPKAPK2 | Thr206 | PNAILKLtDFGFAKE | phosphorylation up-regulates activity | 7592979 | SIGNOR-250101 |
| MAPK14 | DDIT3 | Ser82 | STSQSPHsPDSSQSS | phosphorylation up-regulates activity | 8650547 | SIGNOR-250096 |
| MAPK14 | EIF4EBP1 | Thr46 | GGTLFSTtPGGTRII | phosphorylation down-regulates activity | 11777913 | SIGNOR-250099 |
| MAPK14 | ZAP70 | Thr293 | TLNSDGYtPEPARIT | phosphorylation down-regulates activity | 29440413 | SIGNOR-277384 |
| MAPK14 | ATF2 | Thr69 | SVIVADQtPTPTRFL | phosphorylation up-regulates | 12110590 | SIGNOR-90521 |
| MAPK14 | SLC9A1 | Ser726 | IDPASPQsPESVDLV | phosphorylation up-regulates | 11604491 | SIGNOR-111043 |
| MAPK14 | TP53 | Ser33 | LPENNVLsPLPSQAM | phosphorylation up-regulates activity | 10581258 | SIGNOR-72699 |
| MAPK14 | JDP2 | Thr148 | VRTDSVKtPESEGNP | phosphorylation unknown | 12225289 | SIGNOR-250100 |
| MAPK14 | EZH2 | – | phosphorylation up-regulates activity | 21902831 | SIGNOR-176548 | |
| MAPK14 | GSK3B | Ser389 | ARIQAAAsTPTNATA | phosphorylation down-regulates | 18451303 | SIGNOR-178603 |
| MAPK14 | EEF2K | Ser396 | TFDSLPSsPSSATPH | phosphorylation down-regulates activity | 12171600 | SIGNOR-249707 |
| MAPK14 | MAPKAPK2 | Ser272 | SNHGLAIsPGMKTRI | phosphorylation up-regulates activity | 14499342 | SIGNOR-118036 |
| MAPK14 | NR3C1 | Ser211 | PGKETNEsPWRSDLL | phosphorylation up-regulates | 15817653 | SIGNOR-135198 |
| MAPK14 | BCL2 | Thr56 | FSSQPGHtPHPAASR | phosphorylation down-regulates activity | 16714293 | SIGNOR-146786 |
| MAPK14 | TAB1 | Ser423 | QMVNGAHsASTLDEA | phosphorylation down-regulates activity | 19393267 | SIGNOR-185580 |
| MAPK14 | ATF2 | Thr69 | SVIVADQtPTPTRFL | phosphorylation up-regulates | 10085140 | SIGNOR-65597 |
| MAPK14 | MEF2A | Thr312 | QATQPLAtPVVSVTT | phosphorylation up-regulates activity | 9858528 | SIGNOR-62780 |
| MAPK14 | RPS6KA5 | Ser376 | EKLFQGYsFVAPSIL | phosphorylation up-regulates activity | 15568999 | SIGNOR-249199 |
| MAPK14 | SLC9A1 | Ser723 | VITIDPAsPQSPESV | phosphorylation up-regulates | 11604491 | SIGNOR-111039 |
| MAPK14 | SLC9A1 | Thr718 | KEDLPVItIDPASPQ | phosphorylation up-regulates | 11604491 | SIGNOR-111051 |
| MAPK14 | KHSRP | Thr692 | QAAYYGQtPGPGGPQ | phosphorylation down-regulates activity | 16364914 | SIGNOR-235856 |
| MAPK14 | KRT8 | Ser74 | TVNQSLLsPLVLEVD | phosphorylation up-regulates | 11788583 | SIGNOR-114079 |
| MAPK14 | MEF2C | – | phosphorylation up-regulates activity | 21902831 | SIGNOR-176551 | |
| MAPK14 | TP53 | Ser46 | AMDDLMLsPDDIEQW | phosphorylation up-regulates activity | 10581258 | SIGNOR-72703 |
| MAPK14 | CASP8 | Ser347 | FTGLKCPsLAGKPKV | phosphorylation down-regulates | 14970175 | SIGNOR-122103 |
| MAPK14 | MAPKAPK3 | – | phosphorylation up-regulates activity | 11157753 | SIGNOR-235451 | |
| MAPK14 | MKNK1 | Thr255 | ITTPELTtPCGSAEY | phosphorylation up-regulates | 9155017 | SIGNOR-48346 |
| MAPK14 | F3 | Ser290 | GQSWKENsPLNVS | phosphorylation down-regulates | 23195225 | SIGNOR-199868 |
| MAPK14 | MKNK1 | – | phosphorylation up-regulates activity | 9155018 | SIGNOR-253011 | |
| MAPK14 | USP21 | Ser538 | VYNDSRVsPVSENQV | phosphorylation up-regulates activity | 28254948 | SIGNOR-273670 |
| MAPK14 | STAT3 | Ser727 | NTIDLPMsPRTLDSL | phosphorylation up-regulates | 17502367 | SIGNOR-154783 |
| MAPK14 | ZNHIT1 | Thr103 | AEGPNYLtACAGPPS | phosphorylation up-regulates | 17380123 | SIGNOR-153899 |
| MAPK14 | ATF2 | Ser90 | GLFNELAsPFENEFK | phosphorylation up-regulates activity | 10085140 | SIGNOR-250090 |
| MAPK14 | EGFR | – | phosphorylation down-regulates | 16932740 | SIGNOR-149089 | |
| MAPK14 | ZFP36 | – | phosphorylation down-regulates activity | 25815583 | SIGNOR-253596 | |
| MAPK14 | PTPN7 | Thr66 | EPICSVNtPREVTLH | phosphorylation down-regulates activity | 10206983 | SIGNOR-250110 |
| MAPK14 | MEF2C | Thr300 | TPVVSVAtPTLPGQG | phosphorylation up-regulates activity | 9858528 | SIGNOR-62796 |
| MAPK14 | TAB1 | Thr431 | ASTLDEAtPTLTNQS | phosphorylation down-regulates activity | 19393267 | SIGNOR-185584 |
| MAPK14 | NFATC4 | Ser170 | GGAFFSPsPGSSSLS | phosphorylation down-regulates activity | 11997522 | SIGNOR-250108 |
| MAPK14 | PPARGC1A | Thr299 | AGLTPPTtPPHKANQ | phosphorylation up-regulates | 11741533 | SIGNOR-112774 |
| MAPK14 | MEF2D | – | phosphorylation up-regulates activity | 21902831 | SIGNOR-176554 | |
| MAPK14 | ATF2 | Thr71 | IVADQTPtPTRFLKN | phosphorylation up-regulates | 20068231 | SIGNOR-163250 |
| MAPK14 | CDKN1A | Ser130 | SGEQAEGsPGGPGDS | phosphorylation up-regulates quantity by stabilization | 12058028 | SIGNOR-89436 |
| MAPK14 | RPS6KA4 | Ser343 | TRLEPVYsPPGSPPP | phosphorylation up-regulates | 10806207 | SIGNOR-77208 |
| MAPK14 | STAT4 | Ser721 | PSDLLPMsPSVYAVL | phosphorylation up-regulates | 17502367 | SIGNOR-154787 |
| MAPK14 | ATF2 | Thr69 | SVIVADQtPTPTRFL | phosphorylation up-regulates | 20068231 | SIGNOR-163246 |
| MAPK14 | NFATC4 | Ser168 | QGGGAFFsPSPGSSS | phosphorylation down-regulates activity | 11997522 | SIGNOR-250107 |
| MAPK14 | TP53 | Ser15 | PSVEPPLsQETFSDL | phosphorylation up-regulates | 11258706 | SIGNOR-105737 |
| MAPK14 | SMARCD3 | – | phosphorylation up-regulates activity | 21902831 | SIGNOR-176557 | |
| MAPK14 | EIF4EBP1 | Ser65 | FLMECRNsPVTKTPP | phosphorylation down-regulates activity | 11777913 | SIGNOR-250097 |
| MAPK14 | EEA1 | – | phosphorylation up-regulates | 16138080 | SIGNOR-140085 | |
| MAPK14 | HBP1 | Ser402 | GFSKNCGsPGSSQLS | phosphorylation up-regulates | 14612426 | SIGNOR-119138 |
| MAPK14 | PAK6 | Ser165 | MPWPEPQsPRVLPNG | phosphorylation up-regulates | 15550393 | SIGNOR-130979 |
| MAPK14 | PPARGC1A | Ser266 | SLPLTPEsPNDPKGS | phosphorylation up-regulates | 11741533 | SIGNOR-112766 |
| MAPK14 | MAPKAPK5 | Thr182 | IDQGDLMtPQFTPYY | phosphorylation up-regulates activity | 9628874 | SIGNOR-58135 |
| MAPK14 | MEF2C | Thr293 | QSAQSLAtPVVSVAT | phosphorylation up-regulates activity | 9069290 | SIGNOR-47136 |
| MAPK14 | ELAVL1 | – | phosphorylation up-regulates | 19528229 | SIGNOR-186138 | |
| MAPK14 | ELK3 | Ser357 | IHFWSSLsPVAPLSP | phosphorylation up-regulates | 9130707 | SIGNOR-47681 |
| MAPK14 | PXN | Ser85 | HQQPQSSsPVYGSSA | phosphorylation unknown | 14970194 | SIGNOR-122108 |
| MAPK14 | BCL2 | Ser87 | AAAGPALsPVPPVVH | phosphorylation down-regulates activity | 19336399 | SIGNOR-184936 |
| MAPK14 | TP53 | Ser392 | FKTEGPDsD | phosphorylation up-regulates activity | 10747897 | SIGNOR-250114 |
| MAPK14 | Polycomb repressive complex 2 | – | phosphorylation up-regulates activity | 20887952 | SIGNOR-253599 | |
| MAPK14 | MKNK2 | – | phosphorylation up-regulates | 9155017 | SIGNOR-48349 | |
| MAPK14 | BAZ1B | Ser158 | KSDGACDsPSSDKEN | phosphorylation up-regulates | 19776015 | SIGNOR-188160 |
| MAPK14 | Histone H3 | – | phosphorylation unknown | 10806218 | SIGNOR-265338 | |
| MAPK14 | ELK1 | Ser383 | IHFWSTLsPIAPRSP | phosphorylation up-regulates | 11145955 | SIGNOR-85510 |
| MAPK14 | ELK1 | Ser383 | IHFWSTLsPIAPRSP | phosphorylation up-regulates | 20727996 | SIGNOR-167539 |
| MAPK14 | PIP4K2B | Ser326 | SYGTPPDsPGNLLSF | phosphorylation down-regulates | 16949365 | SIGNOR-149359 |
| MAPK14 | CDX2 | Ser283 | RSVPEPLsPVSSLQA | phosphorylation down-regulates quantity by destabilization | 16027724 | SIGNOR-250092 |
| MAPK14 | TP53 | Ser33 | LPENNVLsPLPSQAM | phosphorylation up-regulates | 22975381 | SIGNOR-192057 |
| MAPK14 | SNX27 | Ser51 | VRIVKSEsGYGFNVR | phosphorylation down-regulates activity | 33605979 | SIGNOR-279069 |
| MAPK14 | EEA1 | Thr1392 | CSAKNALtPSSKKPV | phosphorylation up-regulates activity | 16138080 | SIGNOR-140082 |
| MAPK14 | RPS6KA4 | Ser196 | EEKERTFsFCGTIEY | phosphorylation up-regulates | 10806207 | SIGNOR-77204 |
| MAPK14 | ESR1 | Thr311 | NSLALSLtADQMVSA | phosphorylation up-regulates | 12138194 | SIGNOR-90823 |
| MAPK14 | MAX | – | phosphorylation down-regulates | 7479834 | SIGNOR-26511 | |
| MAPK14 | TP63 | Ser301 | S-->T | phosphorylation down-regulates quantity by destabilization | 30301786 | SIGNOR-277414 |
| MAPK14 | TP53 | Ser15 | PSVEPPLsQETFSDL | phosphorylation up-regulates activity | 10581258 | SIGNOR-72695 |
| MAPK14 | NCOA3 | Ser867 | SPVSVGSsPPVKNIS | phosphorylation up-regulates activity | 15383283 | SIGNOR-250106 |
| MAPK14 | MEF2C | Ser387 | LSLPSTQsLNIKSEP | phosphorylation up-regulates activity | 9858528 | SIGNOR-62788 |
| MAPK14 | TWIST1 | Ser68 | GGGDEPGsPAQGKRG | phosphorylation up-regulates | 21502402 | SIGNOR-173409 |
| MAPK14 | SUZ12/EZH2 | – | phosphorylation up-regulates | 21902831 | SIGNOR-217676 | |
| MAPK14 | ADAM17 | Thr735 | KPFPAPQtPGRLQPA | phosphorylation up-regulates activity | 20188673 | SIGNOR-163970 |
| MAPK14 | RPS6KA5 | Ser360 | TEMDPTYsPAALPQS | phosphorylation up-regulates activity | 15568999 | SIGNOR-130736 |
| MAPK14 | GATA2 | – | phosphorylation up-regulates activity | 25056917 | SIGNOR-259946 | |
| MAPK14 | CDC25C | Ser216 | SGLYRSPsMPENLNR | phosphorylation down-regulates activity | 9543386 | SIGNOR-250091 |
| MAPK14 | FOXO3 | Ser7 | sPAPLSPL | phosphorylation up-regulates | 22128155 | SIGNOR-177927 |
| MAPK14 | RBSN | – | phosphorylation up-regulates | 16138080 | SIGNOR-140146 | |
| MAPK14 | CFLAR | – | phosphorylation up-regulates | 19597496 | SIGNOR-187001 | |
| MAPK14 | RBSN | Ser215 | ESLSTHTsPSQSPNS | phosphorylation up-regulates | 16138080 | SIGNOR-140143 |
| MAPK14 | TP53 | Ser15 | PSVEPPLsQETFSDL | phosphorylation up-regulates quantity by stabilization | 10781582 | SIGNOR-226614 |
| MAPK14 | ELK3 | Ser363 | LSPVAPLsPARLQGP | phosphorylation up-regulates | 9130707 | SIGNOR-47685 |
| MAPK14 | MKNK1 | Thr250 | NSCTPITtPELTTPC | phosphorylation up-regulates activity | 9155017 | SIGNOR-48342 |
| MAPK14 | TP63 | Ser310 | LYNFMCNsSCVGGMN | phosphorylation down-regulates quantity by destabilization | 30301786 | SIGNOR-277414 |
| MAPK14 | RPS6KA5 | – | phosphorylation up-regulates activity | 9687510 | SIGNOR-59454 | |
| MAPK14 | CASP3 | Ser150 | FRGDRCRsLTGKPKL | phosphorylation down-regulates | 14970175 | SIGNOR-122099 |
| MAPK14 | RPS6KA4 | – | phosphorylation up-regulates | 9792677 | SIGNOR-60995 | |
| MAPK14 | BCL2L11 | Ser69 | GPLAPPAsPGPFATR | phosphorylation down-regulates quantity by destabilization | 15486195 | SIGNOR-260442 |
| MAPK14 | TP53BP1 | Thr1609 | LGPYEAVtPLTKAAD | phosphorylation down-regulates activity | 24703952 | SIGNOR-264446 |
| MAPK14 | MAPKAPK2 | Thr334 | QSTKVPQtPLHTSRV | phosphorylation up-regulates activity | 14499342 | SIGNOR-118044 |
| MAPK14 | EIF4EBP1 | Thr37 | PPGDYSTtPGGTLFS | phosphorylation down-regulates activity | 11777913 | SIGNOR-250098 |
| MAPK14 | EPS15 | Ser796 | RSINKLDsPDPFKLN | phosphorylation up-regulates | 24269888 | SIGNOR-203315 |
| MAPK14 | SIAH2 | – | phosphorylation up-regulates | 17003045 | SIGNOR-149890 | |
| MAPK14 | GLI1 | Ser941 | S-->A | phosphorylation down-regulates quantity by destabilization | 38307877 | SIGNOR-277917 |
| MAPK14 | MAPKAPK2 | Thr25 | APPPQPPtPALPHPP | phosphorylation up-regulates activity | 8846784 | SIGNOR-44351 |
| MAPK14 | SLC9A1 | Ser729 | ASPQSPEsVDLVNEE | phosphorylation up-regulates | 11604491 | SIGNOR-111047 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK14 | phosphorylation up-regulates → | FOXC1 PSer272 | phosphorylation up-regulates → | FOXC1 | 31650548 | SIGNOR-275911 |
| MAPK14 | phosphorylation up-regulates → | GLI1 PSer937 | phosphorylation down-regulates ⊣ | GLI1 | 38307877 | SIGNOR-277916 |
| MAPK14 | phosphorylation up-regulates → | GSK3B PSer389 | phosphorylation down-regulates ⊣ | GSK3B | 17726008 | SIGNOR-157548 |
| MAPK14 | phosphorylation up-regulates → | NCOA3 PSer505 | phosphorylation up-regulates → | NCOA3 | 15383283 | SIGNOR-250103 |
| MAPK14 | phosphorylation up-regulates → | ATF6 PThr166 | phosphorylation up-regulates → | ATF6 | 25135476 | SIGNOR-276841 |
| MAPK14 | phosphorylation up-regulates → | ELAVL1 PThr118 | phosphorylation up-regulates → | ELAVL1 | 19528229 | SIGNOR-186135 |
| MAPK14 | phosphorylation up-regulates → | RB1 PSer567 | phosphorylation down-regulates ⊣ | RB1 | 20871633 | SIGNOR-168178 |
| MAPK14 | phosphorylation up-regulates → | NCOA3 PSer543 | phosphorylation up-regulates → | NCOA3 | 15383283 | SIGNOR-250104 |
| MAPK14 | phosphorylation up-regulates → | H3C1 PSer11 | phosphorylation down-regulates ⊣ | H3C1 | 20626350 | SIGNOR-166602 |
| MAPK14 | phosphorylation up-regulates → | TP53 PSer33 | phosphorylation up-regulates → | TP53 | 17535811 | SIGNOR-155242 |
| MAPK14 | phosphorylation up-regulates → | PTPN7 PSer93 | phosphorylation down-regulates ⊣ | PTPN7 | 10206983 | SIGNOR-250109 |
| MAPK14 | phosphorylation up-regulates → | MEF2A PSer408 | phosphorylation down-regulates ⊣ | MEF2A | 12586839 | SIGNOR-98224 |
| MAPK14 | phosphorylation up-regulates → | TP53 PSer46 | phosphorylation up-regulates → | TP53 | 17535811 | SIGNOR-155246 |
| MAPK14 | phosphorylation up-regulates → | NFATC1 PSer172 | phosphorylation down-regulates ⊣ | NFATC1 | 10652349 | SIGNOR-74560 |
| MAPK14 | phosphorylation up-regulates → | FOXO PSer7 | phosphorylation up-regulates → | FOXO | 22128155 | SIGNOR-252960 |
| MAPK14 | phosphorylation up-regulates → | SMAD3 PSer208 | phosphorylation up-regulates → | SMAD3 | 15520018 | SIGNOR-250112 |
| MAPK14 | phosphorylation up-regulates → | CDX2 PSer295 | phosphorylation down-regulates ⊣ | CDX2 | 16027724 | SIGNOR-250095 |
| MAPK14 | phosphorylation up-regulates → | ELK1 PSer383 | phosphorylation up-regulates → | ELK1 | 9130707 | SIGNOR-47630 |
| MAPK14 | phosphorylation up-regulates → | USF1 PThr153 | phosphorylation up-regulates → | USF1 | 19389701 | SIGNOR-185572 |
| MAPK14 | phosphorylation up-regulates → | JUNB PSer79 | phosphorylation up-regulates → | JUNB | 15308641 | SIGNOR-127545 |
| MAPK14 | phosphorylation up-regulates → | TP53 PSer33 | phosphorylation up-regulates → | TP53 | 11258706 | SIGNOR-105741 |
| MAPK14 | phosphorylation up-regulates → | SLC9A1 PSer729 | phosphorylation up-regulates → | SLC9A1 | 18701649 | SIGNOR-180048 |
| MAPK14 | phosphorylation up-regulates → | ELK1 PSer389 | phosphorylation up-regulates → | ELK1 | 9130707 | SIGNOR-47634 |
| MAPK14 | phosphorylation up-regulates → | PIAS2 PSer116 | phosphorylation up-regulates → | PIAS2 | 16713578 | SIGNOR-262949 |
| MAPK14 | phosphorylation up-regulates → | MAPKAPK2 PThr222 | phosphorylation up-regulates → | MAPKAPK2 | 14499342 | SIGNOR-118040 |
| MAPK14 | phosphorylation up-regulates → | MEF2A PThr319 | phosphorylation up-regulates → | MEF2A | 9858528 | SIGNOR-62784 |
| MAPK14 | phosphorylation up-regulates → | NR3C1 PSer211 | phosphorylation up-regulates → | NR3C1 | 20660302 | SIGNOR-255952 |
| MAPK14 | phosphorylation up-regulates → | MEF2A PSer453 | phosphorylation down-regulates ⊣ | MEF2A | 12586839 | SIGNOR-98228 |
| MAPK14 | phosphorylation up-regulates → | EWSR1 PThr79 | phosphorylation down-regulates ⊣ | EWSR1 | 19076070 | SIGNOR-182778 |
| MAPK14 | phosphorylation up-regulates → | ESR1 PSer118 | phosphorylation up-regulates → | ESR1 | 15879307 | SIGNOR-136950 |
| MAPK14 | phosphorylation up-regulates → | STAT3 PSer727 | phosphorylation up-regulates → | STAT3 | 18691976 | SIGNOR-179912 |
| MAPK14 | phosphorylation up-regulates → | NCOA3 PSer860 | phosphorylation up-regulates → | NCOA3 | 15383283 | SIGNOR-250105 |
| MAPK14 | phosphorylation up-regulates → | TP53 PSer46 | phosphorylation up-regulates → | TP53 | 15642743 | SIGNOR-226620 |
| MAPK14 | phosphorylation up-regulates → | TCF3 PSer139 | phosphorylation up-regulates → | TCF3 | 15719023 | SIGNOR-134194 |
| MAPK14 | phosphorylation up-regulates → | SMAD3 PSer204 | phosphorylation up-regulates → | SMAD3 | 15520018 | SIGNOR-250113 |
| MAPK14 | phosphorylation up-regulates → | MEF2C PThr293 | phosphorylation up-regulates → | MEF2C | 9858528 | SIGNOR-62792 |
| MAPK14 | phosphorylation up-regulates → | FGFR1 PSer777 | phosphorylation down-regulates ⊣ | FGFR1 | 20626350 | SIGNOR-166598 |
| MAPK14 | phosphorylation up-regulates → | CDX2 PSer291 | phosphorylation down-regulates ⊣ | CDX2 | 16027724 | SIGNOR-250094 |
| MAPK14 | phosphorylation up-regulates → | STAT1 PSer727 | phosphorylation up-regulates → | STAT1 | 17502367 | SIGNOR-154779 |
| MAPK14 | phosphorylation up-regulates → | KAT5 PThr158 | phosphorylation up-regulates → | KAT5 | 25544752 | SIGNOR-278958 |
| MAPK14 | phosphorylation up-regulates → | RBPJ PThr339 | phosphorylation down-regulates ⊣ | RBPJ | 22302987 | SIGNOR-276403 |
| MAPK14 | phosphorylation up-regulates → | DDIT3 PSer79 | phosphorylation up-regulates → | DDIT3 | 8650547 | SIGNOR-42200 |
| MAPK14 | phosphorylation up-regulates → | AKT2 PSer474 | phosphorylation up-regulates → | AKT2 | 12181443 | SIGNOR-91408 |
| MAPK14 | phosphorylation up-regulates → | DLX5 PSer34 | phosphorylation up-regulates → | DLX5 | 18056716 | SIGNOR-255792 |
| MAPK14 | phosphorylation up-regulates → | CDX2 PSer287 | phosphorylation down-regulates ⊣ | CDX2 | 16027724 | SIGNOR-250093 |
| MAPK14 | phosphorylation up-regulates → | MAPKAPK2 PThr317 | phosphorylation up-regulates → | MAPKAPK2 | 7592979 | SIGNOR-250102 |
| MAPK14 | phosphorylation up-regulates → | RPS6KA4 PSer347 | phosphorylation up-regulates → | RPS6KA4 | 10806207 | SIGNOR-77212 |
| MAPK14 | phosphorylation up-regulates → | PLA2G4A PSer505 | phosphorylation up-regulates → | PLA2G4A | 8910365 | SIGNOR-44673 |
| MAPK14 | phosphorylation up-regulates → | PPARGC1A PThr263 | phosphorylation up-regulates → | PPARGC1A | 11741533 | SIGNOR-112770 |
| MAPK14 | phosphorylation up-regulates → | TAB1 PSer438 | phosphorylation down-regulates ⊣ | TAB1 | 14592977 | SIGNOR-118922 |
| MAPK14 | phosphorylation up-regulates → | EZH2 PThr367 | phosphorylation down-regulates ⊣ | EZH2 | 28067271 | SIGNOR-255663 |
| MAPK14 | phosphorylation up-regulates → | PIAS2 PSer113 | phosphorylation up-regulates → | PIAS2 | 16713578 | SIGNOR-262948 |
| MAPK14 | phosphorylation up-regulates → | FOXC1 PSer241 | phosphorylation up-regulates → | FOXC1 | 31650548 | SIGNOR-275913 |
| MAPK14 | phosphorylation up-regulates → | GLI1 PSer982 | phosphorylation down-regulates ⊣ | GLI1 | 38307877 | SIGNOR-277917 |
| MAPK14 | phosphorylation up-regulates → | RPS6KA5 PThr581 | phosphorylation up-regulates → | RPS6KA5 | 15568999 | SIGNOR-131375 |
| MAPK14 | phosphorylation up-regulates → | ATF2 PThr71 | phosphorylation up-regulates → | ATF2 | 10085140 | SIGNOR-65601 |
| MAPK14 | phosphorylation up-regulates → | RPS6KA4 PSer360 | phosphorylation up-regulates → | RPS6KA4 | 10806207 | SIGNOR-77216 |
| MAPK14 | phosphorylation up-regulates → | SLC9A1 PSer726 | phosphorylation up-regulates → | SLC9A1 | 18701649 | SIGNOR-180044 |
| MAPK14 | phosphorylation up-regulates → | ATF2 PThr71 | phosphorylation up-regulates → | ATF2 | 12110590 | SIGNOR-90525 |
| MAPK14 | phosphorylation up-regulates → | RPS6KA4 PThr568 | phosphorylation up-regulates → | RPS6KA4 | 10806207 | SIGNOR-77220 |
| MAPK14 | phosphorylation up-regulates → | MAPKAPK2 PThr206 | phosphorylation up-regulates → | MAPKAPK2 | 7592979 | SIGNOR-250101 |
| MAPK14 | phosphorylation up-regulates → | DDIT3 PSer82 | phosphorylation up-regulates → | DDIT3 | 8650547 | SIGNOR-250096 |
| MAPK14 | phosphorylation up-regulates → | EIF4EBP1 PThr46 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11777913 | SIGNOR-250099 |
| MAPK14 | phosphorylation up-regulates → | ZAP70 PThr293 | phosphorylation down-regulates ⊣ | ZAP70 | 29440413 | SIGNOR-277384 |
| MAPK14 | phosphorylation up-regulates → | ATF2 PThr69 | phosphorylation up-regulates → | ATF2 | 12110590 | SIGNOR-90521 |
| MAPK14 | phosphorylation up-regulates → | SLC9A1 PSer726 | phosphorylation up-regulates → | SLC9A1 | 11604491 | SIGNOR-111043 |
| MAPK14 | phosphorylation up-regulates → | TP53 PSer33 | phosphorylation up-regulates → | TP53 | 10581258 | SIGNOR-72699 |
| MAPK14 | phosphorylation up-regulates → | JDP2 PThr148 | phosphorylation down-regulates ⊣ | JDP2 | 12225289 | SIGNOR-250100 |
| MAPK14 | phosphorylation up-regulates → | GSK3B PSer389 | phosphorylation down-regulates ⊣ | GSK3B | 18451303 | SIGNOR-178603 |
| MAPK14 | phosphorylation up-regulates → | EEF2K PSer396 | phosphorylation down-regulates ⊣ | EEF2K | 12171600 | SIGNOR-249707 |
| MAPK14 | phosphorylation up-regulates → | MAPKAPK2 PSer272 | phosphorylation up-regulates → | MAPKAPK2 | 14499342 | SIGNOR-118036 |
| MAPK14 | phosphorylation up-regulates → | NR3C1 PSer211 | phosphorylation up-regulates → | NR3C1 | 15817653 | SIGNOR-135198 |
| MAPK14 | phosphorylation up-regulates → | BCL2 PThr56 | phosphorylation down-regulates ⊣ | BCL2 | 16714293 | SIGNOR-146786 |
| MAPK14 | phosphorylation up-regulates → | TAB1 PSer423 | phosphorylation down-regulates ⊣ | TAB1 | 19393267 | SIGNOR-185580 |
| MAPK14 | phosphorylation up-regulates → | ATF2 PThr69 | phosphorylation up-regulates → | ATF2 | 10085140 | SIGNOR-65597 |
| MAPK14 | phosphorylation up-regulates → | MEF2A PThr312 | phosphorylation up-regulates → | MEF2A | 9858528 | SIGNOR-62780 |
| MAPK14 | phosphorylation up-regulates → | RPS6KA5 PSer376 | phosphorylation up-regulates → | RPS6KA5 | 15568999 | SIGNOR-249199 |
| MAPK14 | phosphorylation up-regulates → | SLC9A1 PSer723 | phosphorylation up-regulates → | SLC9A1 | 11604491 | SIGNOR-111039 |
| MAPK14 | phosphorylation up-regulates → | SLC9A1 PThr718 | phosphorylation up-regulates → | SLC9A1 | 11604491 | SIGNOR-111051 |
| MAPK14 | phosphorylation up-regulates → | KHSRP PThr692 | phosphorylation down-regulates ⊣ | KHSRP | 16364914 | SIGNOR-235856 |
| MAPK14 | phosphorylation up-regulates → | KRT8 PSer74 | phosphorylation up-regulates → | KRT8 | 11788583 | SIGNOR-114079 |
| MAPK14 | phosphorylation up-regulates → | TP53 PSer46 | phosphorylation up-regulates → | TP53 | 10581258 | SIGNOR-72703 |
| MAPK14 | phosphorylation up-regulates → | CASP8 PSer347 | phosphorylation down-regulates ⊣ | CASP8 | 14970175 | SIGNOR-122103 |
| MAPK14 | phosphorylation up-regulates → | MKNK1 PThr255 | phosphorylation up-regulates → | MKNK1 | 9155017 | SIGNOR-48346 |
| MAPK14 | phosphorylation up-regulates → | F3 PSer290 | phosphorylation down-regulates ⊣ | F3 | 23195225 | SIGNOR-199868 |
| MAPK14 | phosphorylation up-regulates → | USP21 PSer538 | phosphorylation up-regulates → | USP21 | 28254948 | SIGNOR-273670 |
| MAPK14 | phosphorylation up-regulates → | STAT3 PSer727 | phosphorylation up-regulates → | STAT3 | 17502367 | SIGNOR-154783 |
| MAPK14 | phosphorylation up-regulates → | ZNHIT1 PThr103 | phosphorylation up-regulates → | ZNHIT1 | 17380123 | SIGNOR-153899 |
| MAPK14 | phosphorylation up-regulates → | ATF2 PSer90 | phosphorylation up-regulates → | ATF2 | 10085140 | SIGNOR-250090 |
| MAPK14 | phosphorylation up-regulates → | PTPN7 PThr66 | phosphorylation down-regulates ⊣ | PTPN7 | 10206983 | SIGNOR-250110 |
| MAPK14 | phosphorylation up-regulates → | MEF2C PThr300 | phosphorylation up-regulates → | MEF2C | 9858528 | SIGNOR-62796 |
| MAPK14 | phosphorylation up-regulates → | TAB1 PThr431 | phosphorylation down-regulates ⊣ | TAB1 | 19393267 | SIGNOR-185584 |
| MAPK14 | phosphorylation up-regulates → | NFATC4 PSer170 | phosphorylation down-regulates ⊣ | NFATC4 | 11997522 | SIGNOR-250108 |
| MAPK14 | phosphorylation up-regulates → | PPARGC1A PThr299 | phosphorylation up-regulates → | PPARGC1A | 11741533 | SIGNOR-112774 |
| MAPK14 | phosphorylation up-regulates → | ATF2 PThr71 | phosphorylation up-regulates → | ATF2 | 20068231 | SIGNOR-163250 |
| MAPK14 | phosphorylation up-regulates → | CDKN1A PSer130 | phosphorylation up-regulates → | CDKN1A | 12058028 | SIGNOR-89436 |
| MAPK14 | phosphorylation up-regulates → | RPS6KA4 PSer343 | phosphorylation up-regulates → | RPS6KA4 | 10806207 | SIGNOR-77208 |
| MAPK14 | phosphorylation up-regulates → | STAT4 PSer721 | phosphorylation up-regulates → | STAT4 | 17502367 | SIGNOR-154787 |
| MAPK14 | phosphorylation up-regulates → | ATF2 PThr69 | phosphorylation up-regulates → | ATF2 | 20068231 | SIGNOR-163246 |
| MAPK14 | phosphorylation up-regulates → | NFATC4 PSer168 | phosphorylation down-regulates ⊣ | NFATC4 | 11997522 | SIGNOR-250107 |
| MAPK14 | phosphorylation up-regulates → | TP53 PSer15 | phosphorylation up-regulates → | TP53 | 11258706 | SIGNOR-105737 |
| MAPK14 | phosphorylation up-regulates → | EIF4EBP1 PSer65 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11777913 | SIGNOR-250097 |
| MAPK14 | phosphorylation up-regulates → | HBP1 PSer402 | phosphorylation up-regulates → | HBP1 | 14612426 | SIGNOR-119138 |
| MAPK14 | phosphorylation up-regulates → | PAK6 PSer165 | phosphorylation up-regulates → | PAK6 | 15550393 | SIGNOR-130979 |
| MAPK14 | phosphorylation up-regulates → | PPARGC1A PSer266 | phosphorylation up-regulates → | PPARGC1A | 11741533 | SIGNOR-112766 |
| MAPK14 | phosphorylation up-regulates → | MAPKAPK5 PThr182 | phosphorylation up-regulates → | MAPKAPK5 | 9628874 | SIGNOR-58135 |
| MAPK14 | phosphorylation up-regulates → | MEF2C PThr293 | phosphorylation up-regulates → | MEF2C | 9069290 | SIGNOR-47136 |
| MAPK14 | phosphorylation up-regulates → | ELK3 PSer357 | phosphorylation up-regulates → | ELK3 | 9130707 | SIGNOR-47681 |
| MAPK14 | phosphorylation up-regulates → | PXN PSer85 | phosphorylation down-regulates ⊣ | PXN | 14970194 | SIGNOR-122108 |
| MAPK14 | phosphorylation up-regulates → | BCL2 PSer87 | phosphorylation down-regulates ⊣ | BCL2 | 19336399 | SIGNOR-184936 |
| MAPK14 | phosphorylation up-regulates → | TP53 PSer392 | phosphorylation up-regulates → | TP53 | 10747897 | SIGNOR-250114 |
| MAPK14 | phosphorylation up-regulates → | BAZ1B PSer158 | phosphorylation up-regulates → | BAZ1B | 19776015 | SIGNOR-188160 |
| MAPK14 | phosphorylation up-regulates → | ELK1 PSer383 | phosphorylation up-regulates → | ELK1 | 11145955 | SIGNOR-85510 |
| MAPK14 | phosphorylation up-regulates → | ELK1 PSer383 | phosphorylation up-regulates → | ELK1 | 20727996 | SIGNOR-167539 |
| MAPK14 | phosphorylation up-regulates → | PIP4K2B PSer326 | phosphorylation down-regulates ⊣ | PIP4K2B | 16949365 | SIGNOR-149359 |
| MAPK14 | phosphorylation up-regulates → | CDX2 PSer283 | phosphorylation down-regulates ⊣ | CDX2 | 16027724 | SIGNOR-250092 |
| MAPK14 | phosphorylation up-regulates → | TP53 PSer33 | phosphorylation up-regulates → | TP53 | 22975381 | SIGNOR-192057 |
| MAPK14 | phosphorylation up-regulates → | SNX27 PSer51 | phosphorylation down-regulates ⊣ | SNX27 | 33605979 | SIGNOR-279069 |
| MAPK14 | phosphorylation up-regulates → | EEA1 PThr1392 | phosphorylation up-regulates → | EEA1 | 16138080 | SIGNOR-140082 |
| MAPK14 | phosphorylation up-regulates → | RPS6KA4 PSer196 | phosphorylation up-regulates → | RPS6KA4 | 10806207 | SIGNOR-77204 |
| MAPK14 | phosphorylation up-regulates → | ESR1 PThr311 | phosphorylation up-regulates → | ESR1 | 12138194 | SIGNOR-90823 |
| MAPK14 | phosphorylation up-regulates → | TP63 PSer301 | phosphorylation down-regulates ⊣ | TP63 | 30301786 | SIGNOR-277414 |
| MAPK14 | phosphorylation up-regulates → | TP53 PSer15 | phosphorylation up-regulates → | TP53 | 10581258 | SIGNOR-72695 |
| MAPK14 | phosphorylation up-regulates → | NCOA3 PSer867 | phosphorylation up-regulates → | NCOA3 | 15383283 | SIGNOR-250106 |
| MAPK14 | phosphorylation up-regulates → | MEF2C PSer387 | phosphorylation up-regulates → | MEF2C | 9858528 | SIGNOR-62788 |
| MAPK14 | phosphorylation up-regulates → | TWIST1 PSer68 | phosphorylation up-regulates → | TWIST1 | 21502402 | SIGNOR-173409 |
| MAPK14 | phosphorylation up-regulates → | ADAM17 PThr735 | phosphorylation up-regulates → | ADAM17 | 20188673 | SIGNOR-163970 |
| MAPK14 | phosphorylation up-regulates → | RPS6KA5 PSer360 | phosphorylation up-regulates → | RPS6KA5 | 15568999 | SIGNOR-130736 |
| MAPK14 | phosphorylation up-regulates → | CDC25C PSer216 | phosphorylation down-regulates ⊣ | CDC25C | 9543386 | SIGNOR-250091 |
| MAPK14 | phosphorylation up-regulates → | FOXO3 PSer7 | phosphorylation up-regulates → | FOXO3 | 22128155 | SIGNOR-177927 |
| MAPK14 | phosphorylation up-regulates → | RBSN PSer215 | phosphorylation up-regulates → | RBSN | 16138080 | SIGNOR-140143 |
| MAPK14 | phosphorylation up-regulates → | TP53 PSer15 | phosphorylation up-regulates → | TP53 | 10781582 | SIGNOR-226614 |
| MAPK14 | phosphorylation up-regulates → | ELK3 PSer363 | phosphorylation up-regulates → | ELK3 | 9130707 | SIGNOR-47685 |
| MAPK14 | phosphorylation up-regulates → | MKNK1 PThr250 | phosphorylation up-regulates → | MKNK1 | 9155017 | SIGNOR-48342 |
| MAPK14 | phosphorylation up-regulates → | TP63 PSer310 | phosphorylation down-regulates ⊣ | TP63 | 30301786 | SIGNOR-277414 |
| MAPK14 | phosphorylation up-regulates → | CASP3 PSer150 | phosphorylation down-regulates ⊣ | CASP3 | 14970175 | SIGNOR-122099 |
| MAPK14 | phosphorylation up-regulates → | BCL2L11 PSer69 | phosphorylation down-regulates ⊣ | BCL2L11 | 15486195 | SIGNOR-260442 |
| MAPK14 | phosphorylation up-regulates → | TP53BP1 PThr1609 | phosphorylation down-regulates ⊣ | TP53BP1 | 24703952 | SIGNOR-264446 |
| MAPK14 | phosphorylation up-regulates → | MAPKAPK2 PThr334 | phosphorylation up-regulates → | MAPKAPK2 | 14499342 | SIGNOR-118044 |
| MAPK14 | phosphorylation up-regulates → | EIF4EBP1 PThr37 | phosphorylation down-regulates ⊣ | EIF4EBP1 | 11777913 | SIGNOR-250098 |
| MAPK14 | phosphorylation up-regulates → | EPS15 PSer796 | phosphorylation up-regulates → | EPS15 | 24269888 | SIGNOR-203315 |
| MAPK14 | phosphorylation up-regulates → | GLI1 PSer941 | phosphorylation down-regulates ⊣ | GLI1 | 38307877 | SIGNOR-277917 |
| MAPK14 | phosphorylation up-regulates → | MAPKAPK2 PThr25 | phosphorylation up-regulates → | MAPKAPK2 | 8846784 | SIGNOR-44351 |
| MAPK14 | phosphorylation up-regulates → | SLC9A1 PSer729 | phosphorylation up-regulates → | SLC9A1 | 11604491 | SIGNOR-111047 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK14 | phosphorylation → up-regulates quantity by stabilization | FOXC1 | SIGNOR-275911 |
| MAPK14 | phosphorylation down-regulates quantity by destabilization | GLI1 | SIGNOR-277916 |
| MAPK14 | phosphorylation down-regulates | GSK3B | SIGNOR-157548 |
| MAPK14 | phosphorylation → up-regulates | MAPT | SIGNOR-166611 |
| MAPK14 | phosphorylation → up-regulates activity | NCOA3 | SIGNOR-250103 |
| MAPK14 | phosphorylation → up-regulates activity | ATF6 | SIGNOR-276841 |
| MAPK14 | phosphorylation → up-regulates | ELAVL1 | SIGNOR-186135 |
| MAPK14 | phosphorylation down-regulates | RB1 | SIGNOR-168178 |
| MAPK14 | phosphorylation → up-regulates activity | NCOA3 | SIGNOR-250104 |
| MAPK14 | phosphorylation → up-regulates activity | ATF2 | SIGNOR-65593 |
| MAPK14 | phosphorylation → unknown | H3C1 | SIGNOR-166602 |
| MAPK14 | phosphorylation → up-regulates | TP53 | SIGNOR-155242 |
| MAPK14 | phosphorylation → up-regulates activity | SMAD3 | SIGNOR-236136 |
| MAPK14 | phosphorylation → down-regulates activity | PTPN7 | SIGNOR-250109 |
| MAPK14 | phosphorylation → unknown | MEF2A | SIGNOR-98224 |
| MAPK14 | phosphorylation → up-regulates activity | TP53 | SIGNOR-155246 |
| MAPK14 | phosphorylation down-regulates | NFATC1 | SIGNOR-74560 |
| MAPK14 | phosphorylation → up-regulates | FOXO | SIGNOR-252960 |
| MAPK14 | phosphorylation → up-regulates activity | SMAD3 | SIGNOR-250112 |
| MAPK14 | phosphorylation down-regulates quantity by destabilization | CDX2 | SIGNOR-250095 |
| MAPK14 | phosphorylation → up-regulates | ELK1 | SIGNOR-47630 |
| MAPK14 | phosphorylation → up-regulates activity | USF1 | SIGNOR-185572 |
| MAPK14 | phosphorylation → up-regulates | JUNB | SIGNOR-127545 |
| MAPK14 | phosphorylation → up-regulates | TP53 | SIGNOR-105741 |
| MAPK14 | phosphorylation → up-regulates | SLC9A1 | SIGNOR-180048 |
| MAPK14 | phosphorylation → up-regulates | ELK1 | SIGNOR-47634 |
| MAPK14 | phosphorylation → up-regulates | ZNHIT1 | SIGNOR-165571 |
| MAPK14 | phosphorylation → up-regulates activity | PIAS2 | SIGNOR-262949 |
| MAPK14 | phosphorylation → up-regulates activity | MAPKAPK2 | SIGNOR-118040 |
| MAPK14 | phosphorylation → up-regulates | MEF2A | SIGNOR-62784 |
| MAPK14 | phosphorylation → up-regulates | NR3C1 | SIGNOR-255952 |
| MAPK14 | phosphorylation → unknown | MEF2A | SIGNOR-98228 |
| MAPK14 | phosphorylation → up-regulates activity | SP7 | SIGNOR-255791 |
| MAPK14 | phosphorylation → unknown | EWSR1 | SIGNOR-182778 |
| MAPK14 | phosphorylation → up-regulates | ESR1 | SIGNOR-136950 |
| MAPK14 | phosphorylation → up-regulates | GATA2 | SIGNOR-205242 |
| MAPK14 | phosphorylation → up-regulates | STAT3 | SIGNOR-179912 |
| MAPK14 | phosphorylation → unknown | H3-3A | SIGNOR-77224 |
| MAPK14 | phosphorylation → up-regulates activity | NCOA3 | SIGNOR-250105 |
| MAPK14 | phosphorylation → up-regulates activity | TP53 | SIGNOR-226620 |
| MAPK14 | phosphorylation → up-regulates activity | TCF3 | SIGNOR-134194 |
| MAPK14 | phosphorylation → up-regulates activity | SMAD3 | SIGNOR-250113 |
| MAPK14 | phosphorylation → up-regulates activity | MEF2C | SIGNOR-62792 |
| MAPK14 | phosphorylation → up-regulates activity | RUNX2 | SIGNOR-255777 |
| MAPK14 | phosphorylation down-regulates | FGFR1 | SIGNOR-166598 |
| MAPK14 | phosphorylation down-regulates quantity by destabilization | CDX2 | SIGNOR-250094 |
| MAPK14 | phosphorylation → up-regulates activity | STAT1 | SIGNOR-154779 |
| MAPK14 | phosphorylation → up-regulates activity | KAT5 | SIGNOR-278958 |
| MAPK14 | phosphorylation → up-regulates | CDKN1C | SIGNOR-198390 |
| MAPK14 | phosphorylation down-regulates quantity by destabilization | RBPJ | SIGNOR-276403 |
| MAPK14 | phosphorylation → up-regulates activity | DDIT3 | SIGNOR-42200 |
| MAPK14 | phosphorylation → up-regulates activity | AKT2 | SIGNOR-91408 |
| MAPK14 | phosphorylation → up-regulates activity | DLX5 | SIGNOR-255792 |
| MAPK14 | phosphorylation → up-regulates | CCND1 | SIGNOR-166594 |
| MAPK14 | phosphorylation down-regulates quantity by destabilization | CDX2 | SIGNOR-250093 |
| MAPK14 | phosphorylation → up-regulates activity | MAPKAPK2 | SIGNOR-250102 |
| MAPK14 | phosphorylation → up-regulates | RPS6KA4 | SIGNOR-77212 |
| MAPK14 | phosphorylation → up-regulates activity | PLA2G4A | SIGNOR-44673 |
| MAPK14 | phosphorylation → up-regulates | PPARGC1A | SIGNOR-112770 |
| MAPK14 | phosphorylation → down-regulates activity | TAB1 | SIGNOR-118922 |
| MAPK14 | phosphorylation down-regulates quantity by destabilization | EZH2 | SIGNOR-255663 |
| MAPK14 | phosphorylation → up-regulates activity | PIAS2 | SIGNOR-262948 |
| MAPK14 | phosphorylation → up-regulates quantity by stabilization | FOXC1 | SIGNOR-275913 |
| MAPK14 | phosphorylation down-regulates quantity by destabilization | GLI1 | SIGNOR-277917 |
| MAPK14 | phosphorylation → up-regulates activity | RPS6KA5 | SIGNOR-131375 |
| MAPK14 | phosphorylation → up-regulates | ATF2 | SIGNOR-65601 |
| MAPK14 | phosphorylation → up-regulates | RPS6KA4 | SIGNOR-77216 |
| MAPK14 | phosphorylation → up-regulates | SLC9A1 | SIGNOR-180044 |
| MAPK14 | phosphorylation down-regulates | MAP3K11 | SIGNOR-166605 |
| MAPK14 | phosphorylation → up-regulates | ATF2 | SIGNOR-90525 |
| MAPK14 | phosphorylation → up-regulates | RPS6KA4 | SIGNOR-77220 |
| MAPK14 | phosphorylation → up-regulates activity | MEF2D | SIGNOR-159331 |
| MAPK14 | phosphorylation → up-regulates activity | MAPKAPK2 | SIGNOR-250101 |
| MAPK14 | phosphorylation → up-regulates activity | DDIT3 | SIGNOR-250096 |
| MAPK14 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-250099 |
| MAPK14 | phosphorylation → down-regulates activity | ZAP70 | SIGNOR-277384 |
| MAPK14 | phosphorylation → up-regulates | ATF2 | SIGNOR-90521 |
| MAPK14 | phosphorylation → up-regulates | SLC9A1 | SIGNOR-111043 |
| MAPK14 | phosphorylation → up-regulates activity | TP53 | SIGNOR-72699 |
| MAPK14 | phosphorylation → unknown | JDP2 | SIGNOR-250100 |
| MAPK14 | phosphorylation → up-regulates activity | EZH2 | SIGNOR-176548 |
| MAPK14 | phosphorylation down-regulates | GSK3B | SIGNOR-178603 |
| MAPK14 | phosphorylation → down-regulates activity | EEF2K | SIGNOR-249707 |
| MAPK14 | phosphorylation → up-regulates activity | MAPKAPK2 | SIGNOR-118036 |
| MAPK14 | phosphorylation → up-regulates | NR3C1 | SIGNOR-135198 |
| MAPK14 | phosphorylation → down-regulates activity | BCL2 | SIGNOR-146786 |
| MAPK14 | phosphorylation → down-regulates activity | TAB1 | SIGNOR-185580 |
| MAPK14 | phosphorylation → up-regulates | ATF2 | SIGNOR-65597 |
| MAPK14 | phosphorylation → up-regulates activity | MEF2A | SIGNOR-62780 |
| MAPK14 | phosphorylation → up-regulates activity | RPS6KA5 | SIGNOR-249199 |
| MAPK14 | phosphorylation → up-regulates | SLC9A1 | SIGNOR-111039 |
| MAPK14 | phosphorylation → up-regulates | SLC9A1 | SIGNOR-111051 |
| MAPK14 | phosphorylation → down-regulates activity | KHSRP | SIGNOR-235856 |
| MAPK14 | phosphorylation → up-regulates | KRT8 | SIGNOR-114079 |
| MAPK14 | phosphorylation → up-regulates activity | MEF2C | SIGNOR-176551 |
| MAPK14 | phosphorylation → up-regulates activity | TP53 | SIGNOR-72703 |
| MAPK14 | phosphorylation down-regulates | CASP8 | SIGNOR-122103 |
| MAPK14 | phosphorylation → up-regulates activity | MAPKAPK3 | SIGNOR-235451 |
| MAPK14 | phosphorylation → up-regulates | MKNK1 | SIGNOR-48346 |
| MAPK14 | phosphorylation down-regulates | F3 | SIGNOR-199868 |
| MAPK14 | phosphorylation → up-regulates activity | MKNK1 | SIGNOR-253011 |
| MAPK14 | phosphorylation → up-regulates activity | USP21 | SIGNOR-273670 |
| MAPK14 | phosphorylation → up-regulates | STAT3 | SIGNOR-154783 |
| MAPK14 | phosphorylation → up-regulates | ZNHIT1 | SIGNOR-153899 |
| MAPK14 | phosphorylation → up-regulates activity | ATF2 | SIGNOR-250090 |
| MAPK14 | phosphorylation down-regulates | EGFR | SIGNOR-149089 |
| MAPK14 | phosphorylation → down-regulates activity | ZFP36 | SIGNOR-253596 |
| MAPK14 | phosphorylation → down-regulates activity | PTPN7 | SIGNOR-250110 |
| MAPK14 | phosphorylation → up-regulates activity | MEF2C | SIGNOR-62796 |
| MAPK14 | phosphorylation → down-regulates activity | TAB1 | SIGNOR-185584 |
| MAPK14 | phosphorylation → down-regulates activity | NFATC4 | SIGNOR-250108 |
| MAPK14 | phosphorylation → up-regulates | PPARGC1A | SIGNOR-112774 |
| MAPK14 | phosphorylation → up-regulates activity | MEF2D | SIGNOR-176554 |
| MAPK14 | phosphorylation → up-regulates | ATF2 | SIGNOR-163250 |
| MAPK14 | phosphorylation → up-regulates quantity by stabilization | CDKN1A | SIGNOR-89436 |
| MAPK14 | phosphorylation → up-regulates | RPS6KA4 | SIGNOR-77208 |
| MAPK14 | phosphorylation → up-regulates | STAT4 | SIGNOR-154787 |
| MAPK14 | phosphorylation → up-regulates | ATF2 | SIGNOR-163246 |
| MAPK14 | phosphorylation → down-regulates activity | NFATC4 | SIGNOR-250107 |
| MAPK14 | phosphorylation → up-regulates | TP53 | SIGNOR-105737 |
| MAPK14 | phosphorylation → up-regulates activity | SMARCD3 | SIGNOR-176557 |
| MAPK14 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-250097 |
| MAPK14 | phosphorylation → up-regulates | EEA1 | SIGNOR-140085 |
| MAPK14 | phosphorylation → up-regulates | HBP1 | SIGNOR-119138 |
| MAPK14 | phosphorylation → up-regulates | PAK6 | SIGNOR-130979 |
| MAPK14 | phosphorylation → up-regulates | PPARGC1A | SIGNOR-112766 |
| MAPK14 | phosphorylation → up-regulates activity | MAPKAPK5 | SIGNOR-58135 |
| MAPK14 | phosphorylation → up-regulates activity | MEF2C | SIGNOR-47136 |
| MAPK14 | phosphorylation → up-regulates | ELAVL1 | SIGNOR-186138 |
| MAPK14 | phosphorylation → up-regulates | ELK3 | SIGNOR-47681 |
| MAPK14 | phosphorylation → unknown | PXN | SIGNOR-122108 |
| MAPK14 | phosphorylation → down-regulates activity | BCL2 | SIGNOR-184936 |
| MAPK14 | phosphorylation → up-regulates activity | TP53 | SIGNOR-250114 |
| MAPK14 | phosphorylation → up-regulates activity | Polycomb repressive complex 2 | SIGNOR-253599 |
| MAPK14 | phosphorylation → up-regulates | MKNK2 | SIGNOR-48349 |
| MAPK14 | phosphorylation → up-regulates | BAZ1B | SIGNOR-188160 |
| MAPK14 | phosphorylation → unknown | Histone H3 | SIGNOR-265338 |
| MAPK14 | phosphorylation → up-regulates | ELK1 | SIGNOR-85510 |
| MAPK14 | phosphorylation → up-regulates | ELK1 | SIGNOR-167539 |
| MAPK14 | phosphorylation down-regulates | PIP4K2B | SIGNOR-149359 |
| MAPK14 | phosphorylation down-regulates quantity by destabilization | CDX2 | SIGNOR-250092 |
| MAPK14 | phosphorylation → up-regulates | TP53 | SIGNOR-192057 |
| MAPK14 | phosphorylation → down-regulates activity | SNX27 | SIGNOR-279069 |
| MAPK14 | phosphorylation → up-regulates activity | EEA1 | SIGNOR-140082 |
| MAPK14 | phosphorylation → up-regulates | RPS6KA4 | SIGNOR-77204 |
| MAPK14 | phosphorylation → up-regulates | ESR1 | SIGNOR-90823 |
| MAPK14 | phosphorylation down-regulates | MAX | SIGNOR-26511 |
| MAPK14 | phosphorylation down-regulates quantity by destabilization | TP63 | SIGNOR-277414 |
| MAPK14 | phosphorylation → up-regulates activity | TP53 | SIGNOR-72695 |
| MAPK14 | phosphorylation → up-regulates activity | NCOA3 | SIGNOR-250106 |
| MAPK14 | phosphorylation → up-regulates activity | MEF2C | SIGNOR-62788 |
| MAPK14 | phosphorylation → up-regulates | TWIST1 | SIGNOR-173409 |
| MAPK14 | phosphorylation → up-regulates | SUZ12/EZH2 | SIGNOR-217676 |
| MAPK14 | phosphorylation → up-regulates activity | ADAM17 | SIGNOR-163970 |
| MAPK14 | phosphorylation → up-regulates activity | RPS6KA5 | SIGNOR-130736 |
| MAPK14 | phosphorylation → up-regulates activity | GATA2 | SIGNOR-259946 |
| MAPK14 | phosphorylation → down-regulates activity | CDC25C | SIGNOR-250091 |
| MAPK14 | phosphorylation → up-regulates | FOXO3 | SIGNOR-177927 |
| MAPK14 | phosphorylation → up-regulates | RBSN | SIGNOR-140146 |
| MAPK14 | phosphorylation → up-regulates | CFLAR | SIGNOR-187001 |
| MAPK14 | phosphorylation → up-regulates | RBSN | SIGNOR-140143 |
| MAPK14 | phosphorylation → up-regulates quantity by stabilization | TP53 | SIGNOR-226614 |
| MAPK14 | phosphorylation → up-regulates | ELK3 | SIGNOR-47685 |
| MAPK14 | phosphorylation → up-regulates activity | MKNK1 | SIGNOR-48342 |
| MAPK14 | phosphorylation down-regulates quantity by destabilization | TP63 | SIGNOR-277414 |
| MAPK14 | phosphorylation → up-regulates activity | RPS6KA5 | SIGNOR-59454 |
| MAPK14 | phosphorylation down-regulates | CASP3 | SIGNOR-122099 |
| MAPK14 | phosphorylation → up-regulates | RPS6KA4 | SIGNOR-60995 |
| MAPK14 | phosphorylation down-regulates quantity by destabilization | BCL2L11 | SIGNOR-260442 |
| MAPK14 | phosphorylation → down-regulates activity | TP53BP1 | SIGNOR-264446 |
| MAPK14 | phosphorylation → up-regulates activity | MAPKAPK2 | SIGNOR-118044 |
| MAPK14 | phosphorylation → down-regulates activity | EIF4EBP1 | SIGNOR-250098 |
| MAPK14 | phosphorylation → up-regulates | EPS15 | SIGNOR-203315 |
| MAPK14 | phosphorylation → up-regulates | SIAH2 | SIGNOR-149890 |
| MAPK14 | phosphorylation down-regulates quantity by destabilization | GLI1 | SIGNOR-277917 |
| MAPK14 | phosphorylation → up-regulates activity | MAPKAPK2 | SIGNOR-44351 |
| MAPK14 | phosphorylation → up-regulates | SLC9A1 | SIGNOR-111047 |