| Name | MAP3K11 |
| ID | Q16584 |
| Role | kinase |
| Enzymatic Domains |
SH3 41-105 PROSITE-ProRule
Protein kinase 117-379 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAP3K11 | MAP2K4 | Thr261 | LVDSIAKtRDAGCRP | phosphorylation up-regulates | 10727406 | SIGNOR-75836 |
| MAP3K11 | MAP2K4 | Ser257 | ISGQLVDsIAKTRDA | phosphorylation up-regulates | 15328343 | SIGNOR-128420 |
| MAP3K11 | MAP2K4 | Ser257 | ISGQLVDsIAKTRDA | phosphorylation up-regulates activity | 9003778 | SIGNOR-48574 |
| MAP3K11 | MAP2K3 | – | phosphorylation up-regulates activity | 9003778 | SIGNOR-45788 | |
| MAP3K11 | MAP2K1 | – | phosphorylation up-regulates activity | 12738796 | SIGNOR-280019 | |
| MAP3K11 | GOLGA3 | – | phosphorylation up-regulates activity | 14734651 | SIGNOR-279065 | |
| MAP3K11 | PAK1 | Ser133 | DVLEFYNsKKTSNSQ | phosphorylation up-regulates activity | 30664689 | SIGNOR-279418 |
| MAP3K11 | PAK1 | Ser204 | TKSVYTRsVIEPLPV | phosphorylation up-regulates activity | 30664689 | SIGNOR-279417 |
| MAP3K11 | PIN1 | Ser138 | QKPFEDAsFALRTGE | phosphorylation up-regulates | 25519816 | SIGNOR-205586 |
| MAP3K11 | MAP3K11 | Ser281 | WHKTTQMsAAGTYAW | phosphorylation up-regulates | 11053428 | SIGNOR-83407 |
| MAP3K11 | MAP3K11 | Thr277 | LAREWHKtTQMSAAG | phosphorylation up-regulates | 11053428 | SIGNOR-83411 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAP3K11 | phosphorylation up-regulates → | MAP2K4 PThr261 | phosphorylation up-regulates → | MAP2K4 | 10727406 | SIGNOR-75836 |
| MAP3K11 | phosphorylation up-regulates → | MAP2K4 PSer257 | phosphorylation up-regulates → | MAP2K4 | 15328343 | SIGNOR-128420 |
| MAP3K11 | phosphorylation up-regulates → | MAP2K4 PSer257 | phosphorylation up-regulates → | MAP2K4 | 9003778 | SIGNOR-48574 |
| MAP3K11 | phosphorylation up-regulates → | PAK1 PSer133 | phosphorylation up-regulates → | PAK1 | 30664689 | SIGNOR-279418 |
| MAP3K11 | phosphorylation up-regulates → | PAK1 PSer204 | phosphorylation up-regulates → | PAK1 | 30664689 | SIGNOR-279417 |
| MAP3K11 | phosphorylation up-regulates → | PIN1 PSer138 | phosphorylation up-regulates → | PIN1 | 25519816 | SIGNOR-205586 |
| MAP3K11 | phosphorylation up-regulates → | MAP3K11 PSer281 | phosphorylation up-regulates → | MAP3K11 | 11053428 | SIGNOR-83407 |
| MAP3K11 | phosphorylation up-regulates → | MAP3K11 PThr277 | phosphorylation up-regulates → | MAP3K11 | 11053428 | SIGNOR-83411 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAP3K11 | phosphorylation → up-regulates | MAP2K4 | SIGNOR-75836 |
| MAP3K11 | phosphorylation → up-regulates | MAP2K4 | SIGNOR-128420 |
| MAP3K11 | phosphorylation → up-regulates activity | MAP2K4 | SIGNOR-48574 |
| MAP3K11 | phosphorylation → up-regulates activity | MAP2K3 | SIGNOR-45788 |
| MAP3K11 | phosphorylation → up-regulates activity | MAP2K1 | SIGNOR-280019 |
| MAP3K11 | phosphorylation → up-regulates activity | GOLGA3 | SIGNOR-279065 |
| MAP3K11 | phosphorylation → up-regulates activity | PAK1 | SIGNOR-279418 |
| MAP3K11 | phosphorylation → up-regulates activity | PAK1 | SIGNOR-279417 |
| MAP3K11 | phosphorylation → up-regulates | PIN1 | SIGNOR-205586 |
| MAP3K11 | phosphorylation → up-regulates | MAP3K11 | SIGNOR-83407 |
| MAP3K11 | phosphorylation → up-regulates | MAP3K11 | SIGNOR-83411 |