| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK3 | HIF1A | Ser657 | ETTSATSsPYRDTQS | phosphorylation down-regulates | 18519666 | SIGNOR-178743 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK3 | phosphorylation up-regulates → | HIF1A PSer657 | phosphorylation down-regulates ⊣ | HIF1A | 18519666 | SIGNOR-178743 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PLK3 | phosphorylation down-regulates | HIF1A | SIGNOR-178743 |
