| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LRRK2 | LRRK2 | Thr1491 | DYHFVNAtEESDALA | phosphorylation down-regulates | 19824698 | SIGNOR-188425 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LRRK2 | phosphorylation up-regulates → | LRRK2 PThr1491 | phosphorylation down-regulates ⊣ | LRRK2 | 19824698 | SIGNOR-188425 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| LRRK2 | phosphorylation down-regulates | LRRK2 | SIGNOR-188425 |
