| Name | FBXO31 |
| ID | Q5XUX0 |
| Role | substrate |
| Enzymatic Domains |
F-box 64-110 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | FBXO31 | Ser33 | AETAAADsEPDTDPE | phosphorylation down-regulates quantity by destabilization | 29343641 | SIGNOR-277376 |
| ATM | FBXO31 | Ser278 | LMKFIYTsQYDNCLT | phosphorylation up-regulates | 19412162 | SIGNOR-185635 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | phosphorylation up-regulates → | FBXO31 PSer33 | phosphorylation down-regulates ⊣ | FBXO31 | 29343641 | SIGNOR-277376 |
| ATM | phosphorylation up-regulates → | FBXO31 PSer278 | phosphorylation up-regulates → | FBXO31 | 19412162 | SIGNOR-185635 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT1 | phosphorylation down-regulates quantity by destabilization | FBXO31 | SIGNOR-277376 |
| ATM | phosphorylation → up-regulates | FBXO31 | SIGNOR-185635 |