3.0
Summary
| Name |  FBXO31View Modifications |
| Full Name | F-box only protein 31 |
| Synonyms | FBX31_HUMAN | FBX14, FBX31 |
| Primary ID | Q5XUX0 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. May act as a tumor suppressor. |
phosphorylation