Entity Details

Name SIGIRR
ID Q6IA17
Role substrate
Enzymatic Domains
Ig-like C2-type 9-109
TIR 163-307
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GSK3BSIGIRRThr372EPSAPPHtSGVSLGEphosphorylation
down-regulates quantity by destabilization
33400290SIGNOR-279053
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GSK3Bphosphorylation
up-regulates
SIGIRR
PThr372
phosphorylation
down-regulates
SIGIRR33400290SIGNOR-279053
Regulator Mechanism/Effect Target SIGNOR-ID
GSK3Bphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
SIGIRRSIGNOR-279053