| Name | KSR2 |
| ID | Q6VAB6 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 666-931 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP3CC | KSR2 | Thr290 | NKLKPPGtPPPSSRK | dephosphorylation up-regulates activity | 19560418 | SIGNOR-248526 |
| PPP3CC | KSR2 | Ser313 | TALHRSKsHEFQLGH | dephosphorylation up-regulates activity | 19560418 | SIGNOR-248527 |
| PPP3CB | KSR2 | Ser198 | IRTHLSQsPRVPSKC | dephosphorylation up-regulates activity | 19560418 | SIGNOR-248380 |
| PPP3CB | KSR2 | Thr290 | NKLKPPGtPPPSSRK | dephosphorylation up-regulates activity | 19560418 | SIGNOR-248381 |
| PPP3CC | KSR2 | Ser198 | IRTHLSQsPRVPSKC | dephosphorylation up-regulates activity | 19560418 | SIGNOR-248525 |
| PPP3CB | KSR2 | Ser313 | TALHRSKsHEFQLGH | dephosphorylation up-regulates activity | 19560418 | SIGNOR-248382 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP3CC | dephosphorylation down-regulates ⊣ | KSR2 PThr290 | dephosphorylation down-regulates ⊣ | KSR2 | 19560418 | SIGNOR-248526 |
| PPP3CC | dephosphorylation down-regulates ⊣ | KSR2 PSer313 | dephosphorylation down-regulates ⊣ | KSR2 | 19560418 | SIGNOR-248527 |
| PPP3CB | dephosphorylation down-regulates ⊣ | KSR2 PSer198 | dephosphorylation down-regulates ⊣ | KSR2 | 19560418 | SIGNOR-248380 |
| PPP3CB | dephosphorylation down-regulates ⊣ | KSR2 PThr290 | dephosphorylation down-regulates ⊣ | KSR2 | 19560418 | SIGNOR-248381 |
| PPP3CC | dephosphorylation down-regulates ⊣ | KSR2 PSer198 | dephosphorylation down-regulates ⊣ | KSR2 | 19560418 | SIGNOR-248525 |
| PPP3CB | dephosphorylation down-regulates ⊣ | KSR2 PSer313 | dephosphorylation down-regulates ⊣ | KSR2 | 19560418 | SIGNOR-248382 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP3CC | dephosphorylation → up-regulates activity | KSR2 | SIGNOR-248526 |
| PPP3CC | dephosphorylation → up-regulates activity | KSR2 | SIGNOR-248527 |
| PPP3CB | dephosphorylation → up-regulates activity | KSR2 | SIGNOR-248380 |
| PPP3CB | dephosphorylation → up-regulates activity | KSR2 | SIGNOR-248381 |
| PPP3CC | dephosphorylation → up-regulates activity | KSR2 | SIGNOR-248525 |
| PPP3CB | dephosphorylation → up-regulates activity | KSR2 | SIGNOR-248382 |