| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP3CB | KSR2 | Ser313 | TALHRSKsHEFQLGH | dephosphorylation up-regulates activity | 19560418 | SIGNOR-248382 |
| PPP3CC | KSR2 | Ser313 | TALHRSKsHEFQLGH | dephosphorylation up-regulates activity | 19560418 | SIGNOR-248527 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP3CB | dephosphorylation down-regulates ⊣ | KSR2 PSer313 | dephosphorylation down-regulates ⊣ | KSR2 | 19560418 | SIGNOR-248382 |
| PPP3CC | dephosphorylation down-regulates ⊣ | KSR2 PSer313 | dephosphorylation down-regulates ⊣ | KSR2 | 19560418 | SIGNOR-248527 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP3CB | dephosphorylation → up-regulates activity | KSR2 | SIGNOR-248382 |
| PPP3CC | dephosphorylation → up-regulates activity | KSR2 | SIGNOR-248527 |