| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | NOXA1 | Ser282 | VGKQAPLsPGLPAMG | phosphorylation down-regulates | 20110267 | SIGNOR-163659 |
| MAPK1 | NOXA1 | Ser282 | VGKQAPLsPGLPAMG | phosphorylation down-regulates | 20230789 | SIGNOR-164227 |
| MAPK3 | NOXA1 | Ser282 | VGKQAPLsPGLPAMG | phosphorylation down-regulates | 20230789 | SIGNOR-164231 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | phosphorylation up-regulates → | NOXA1 PSer282 | phosphorylation down-regulates ⊣ | NOXA1 | 20110267 | SIGNOR-163659 |
| MAPK1 | phosphorylation up-regulates → | NOXA1 PSer282 | phosphorylation down-regulates ⊣ | NOXA1 | 20230789 | SIGNOR-164227 |
| MAPK3 | phosphorylation up-regulates → | NOXA1 PSer282 | phosphorylation down-regulates ⊣ | NOXA1 | 20230789 | SIGNOR-164231 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK1 | phosphorylation down-regulates | NOXA1 | SIGNOR-163659 |
| MAPK1 | phosphorylation down-regulates | NOXA1 | SIGNOR-164227 |
| MAPK3 | phosphorylation down-regulates | NOXA1 | SIGNOR-164231 |
