Summary

Name NOXA1
Full Name NADPH oxidase activator 1
Synonyms NOX activator 1, Antigen NY-CO-31, NCF2-like protein, P67phox-like factor, p51-nox | P51NOX
Primary ID Q86UR1
Links - -
Type protein
Relations 8
Pathways Mitochondrial Control of Apoptosis
Function Functions as an activator of NOX1, a superoxide-producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3.

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png phosphorylation NOXA1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation NOXA1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation NOXA1 0.2
Publications: 2 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation NOXA1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation NOXA1 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation NOXA1 0.22
Publications: 1 Organism: Homo Sapiens
Pathways:Mitochondrial Control of Apoptosis
+ down-regulates activity img/direct_inhibition.png BCL2 0.22
Publications: 1 Organism: Homo Sapiens
Pathways:Mitochondrial Control of Apoptosis