| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | NOXA1 | Ser172 | DQVQRRGsLPPRQVP | phosphorylation down-regulates | 20110267 | SIGNOR-163667 |
| PKA | NOXA1 | Ser172 | DQVQRRGsLPPRQVP | phosphorylation down-regulates activity | 20943948 | SIGNOR-264712 |
| PRKACA | NOXA1 | Ser172 | DQVQRRGsLPPRQVP | phosphorylation down-regulates | 20110267 | SIGNOR-163663 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | phosphorylation up-regulates → | NOXA1 PSer172 | phosphorylation down-regulates ⊣ | NOXA1 | 20110267 | SIGNOR-163667 |
| PKA | phosphorylation up-regulates → | NOXA1 PSer172 | phosphorylation down-regulates ⊣ | NOXA1 | 20943948 | SIGNOR-264712 |
| PRKACA | phosphorylation up-regulates → | NOXA1 PSer172 | phosphorylation down-regulates ⊣ | NOXA1 | 20110267 | SIGNOR-163663 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCA | phosphorylation![]() down-regulates | NOXA1 | SIGNOR-163667 |
| PKA | phosphorylation → down-regulates activity | NOXA1 | SIGNOR-264712 |
| PRKACA | phosphorylation![]() down-regulates | NOXA1 | SIGNOR-163663 |