Entity Details

Name PIM3
ID Q86V86
Role kinase
Enzymatic Domains
Protein kinase 40-293
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PIM3NFATC1–phosphorylation
up-regulates activity		31730483SIGNOR-276773
PIM3CXCR4Ser339GKRGGHSsVSTESESphosphorylation
up-regulates quantity		26075720SIGNOR-279092
PIM3PSMD2Ser361ENNRFGGsGSQVDSAphosphorylation
up-regulates activity		31843888SIGNOR-273897
PIM3BADSer118GRELRRMsDEFVDSFphosphorylation
down-regulates activity		16403219SIGNOR-250396
PIM3BADSer75EIRSRHSsYPAGTEDphosphorylation
down-regulates activity		16403219SIGNOR-249605
PIM3BADSer99PFRGRSRsAPPNLWAphosphorylation
down-regulates activity		16403219SIGNOR-250399
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PIM3phosphorylation
up-regulates
→
CXCR4
PSer339		phosphorylation
up-regulates
→		CXCR426075720SIGNOR-279092
PIM3phosphorylation
up-regulates
→
PSMD2
PSer361		phosphorylation
up-regulates
→		PSMD231843888SIGNOR-273897
PIM3phosphorylation
up-regulates
→
BAD
PSer118		phosphorylation
down-regulates
⊣		BAD16403219SIGNOR-250396
PIM3phosphorylation
up-regulates
→
BAD
PSer75		phosphorylation
down-regulates
⊣		BAD16403219SIGNOR-249605
PIM3phosphorylation
up-regulates
→
BAD
PSer99		phosphorylation
down-regulates
⊣		BAD16403219SIGNOR-250399
Regulator Mechanism/Effect Target SIGNOR-ID
PIM3phosphorylation
→
up-regulates activity 		NFATC1SIGNOR-276773
PIM3phosphorylation
→
up-regulates quantity 		CXCR4SIGNOR-279092
PIM3phosphorylation
→
up-regulates activity 		PSMD2SIGNOR-273897
PIM3phosphorylation
→
down-regulates activity 		BADSIGNOR-250396
PIM3phosphorylation
→
down-regulates activity 		BADSIGNOR-249605
PIM3phosphorylation
→
down-regulates activity 		BADSIGNOR-250399