Entity Details

Name STING1
ID Q86WV6
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAP3K7STING1Ser355TSAVPSTsTMSQEPEphosphorylation
up-regulates activity		37832545SIGNOR-277887
PPM1ASTING1Ser358VPSTSTMsQEPELLIdephosphorylation
down-regulates activity		25815785SIGNOR-276958
ULK1STING1Ser366QEPELLIsGMEKPLPphosphorylation
down-regulates activity		24119841SIGNOR-279316
TBK1STING1Ser358VPSTSTMsQEPELLIphosphorylation
up-regulates activity		18818105SIGNOR-263136
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAP3K7phosphorylation
up-regulates
→
STING1
PSer355		phosphorylation
up-regulates
→		STING137832545SIGNOR-277887
PPM1Adephosphorylation
down-regulates
⊣
STING1
PSer358		dephosphorylation
up-regulates
→		STING125815785SIGNOR-276958
ULK1phosphorylation
up-regulates
→
STING1
PSer366		phosphorylation
down-regulates
⊣		STING124119841SIGNOR-279316
TBK1phosphorylation
up-regulates
→
STING1
PSer358		phosphorylation
up-regulates
→		STING118818105SIGNOR-263136
Regulator Mechanism/Effect Target SIGNOR-ID
MAP3K7phosphorylation
→
up-regulates activity 		STING1SIGNOR-277887
PPM1Adephosphorylation
→
down-regulates activity 		STING1SIGNOR-276958
ULK1phosphorylation
→
down-regulates activity 		STING1SIGNOR-279316
TBK1phosphorylation
→
up-regulates activity 		STING1SIGNOR-263136