| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MTOR | RPTOR | Ser859 | DTSSLTQsAPASPTN | phosphorylation up-regulates activity | 19864431 | SIGNOR-188920 |
| MTOR | RPTOR | Ser859 | DTSSLTQsAPASPTN | phosphorylation up-regulates activity | 19346248 | SIGNOR-184959 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MTOR | phosphorylation up-regulates → | RPTOR PSer859 | phosphorylation up-regulates → | RPTOR | 19864431 | SIGNOR-188920 |
| MTOR | phosphorylation up-regulates → | RPTOR PSer859 | phosphorylation up-regulates → | RPTOR | 19346248 | SIGNOR-184959 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MTOR | phosphorylation → up-regulates activity | RPTOR | SIGNOR-188920 |
| MTOR | phosphorylation → up-regulates activity | RPTOR | SIGNOR-184959 |
