Entity Details

Name CCNY
ID Q8ND76
Role substrate
Enzymatic Domains
Cyclin N-terminal 143-265
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1CCNY–phosphorylation
down-regulates activity		30154440SIGNOR-279012
CyclinY/CDK14CCNYSer73STIFLSKsQTDVREKphosphorylation
down-regulates quantity by destabilization		24794231SIGNOR-273009
PRKAA1CCNYSer326
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SARKRSAsADNLTLPphosphorylation
up-regulates activity		32723157SIGNOR-273011
AMPKCCNYSer326
View in OncoXplorer
SARKRSAsADNLTLPphosphorylation
up-regulates activity		32723157SIGNOR-273001
CDK14CCNYSer71RASTIFLsKSQTDVRphosphorylation
down-regulates quantity by destabilization		24794231SIGNOR-273008
CyclinY/CDK14CCNYSer71RASTIFLsKSQTDVRphosphorylation
down-regulates quantity by destabilization		24794231SIGNOR-273010
CDK14CCNYSer73STIFLSKsQTDVREKphosphorylation
down-regulates quantity by destabilization		24794231SIGNOR-273007
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CyclinY/CDK14phosphorylation
up-regulates
→
CCNY
PSer73		phosphorylation
down-regulates
⊣		CCNY24794231SIGNOR-273009
PRKAA1phosphorylation
up-regulates
→
CCNY
PSer326		phosphorylation
up-regulates
→		CCNY32723157SIGNOR-273011
AMPKphosphorylation
up-regulates
→
CCNY
PSer326		phosphorylation
up-regulates
→		CCNY32723157SIGNOR-273001
CDK14phosphorylation
up-regulates
→
CCNY
PSer71		phosphorylation
down-regulates
⊣		CCNY24794231SIGNOR-273008
CyclinY/CDK14phosphorylation
up-regulates
→
CCNY
PSer71		phosphorylation
down-regulates
⊣		CCNY24794231SIGNOR-273010
CDK14phosphorylation
up-regulates
→
CCNY
PSer73		phosphorylation
down-regulates
⊣		CCNY24794231SIGNOR-273007
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
→
down-regulates activity 		CCNYSIGNOR-279012
CyclinY/CDK14phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CCNYSIGNOR-273009
PRKAA1phosphorylation
→
up-regulates activity 		CCNYSIGNOR-273011
AMPKphosphorylation
→
up-regulates activity 		CCNYSIGNOR-273001
CDK14phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CCNYSIGNOR-273008
CyclinY/CDK14phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CCNYSIGNOR-273010
CDK14phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CCNYSIGNOR-273007