| Name | PREX1 |
| ID | Q8TCU6 |
| Role | substrate |
| Enzymatic Domains |
DH 49-240 PROSITE-ProRule
PH 271-392 PROSITE-ProRule
DEP 1 421-496 PROSITE-ProRule
DEP 2 523-597 PROSITE-ProRule
PDZ 625-703 PROSITE-ProRule |
View in  |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP1CA | PREX1 | Ser834 | LSLGPRLsLCEDSPM | dephosphorylation up-regulates activity | 22242915 | SIGNOR-277022 |
| PPP1CA | PREX1 | Ser1165 | DSGHDTMsYRDSYSE | dephosphorylation up-regulates activity | 22242915 | SIGNOR-277023 |
| PPP1CA | PREX1 | Ser1001 | IRFGRKPsLIGLDPE | dephosphorylation up-regulates activity | 22242915 | SIGNOR-277024 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP1CA | dephosphorylation down-regulates ⊣ | PREX1 PSer834 | dephosphorylation down-regulates ⊣ | PREX1 | 22242915 | SIGNOR-277022 |
| PPP1CA | dephosphorylation down-regulates ⊣ | PREX1 PSer1165 | dephosphorylation down-regulates ⊣ | PREX1 | 22242915 | SIGNOR-277023 |
| PPP1CA | dephosphorylation down-regulates ⊣ | PREX1 PSer1001 | dephosphorylation down-regulates ⊣ | PREX1 | 22242915 | SIGNOR-277024 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP1CA | dephosphorylation → up-regulates activity | PREX1 | SIGNOR-277022 |
| PPP1CA | dephosphorylation → up-regulates activity | PREX1 | SIGNOR-277023 |
| PPP1CA | dephosphorylation → up-regulates activity | PREX1 | SIGNOR-277024 |