| Name | PARD3 |
| ID | Q8TEW0 |
| Role | substrate |
| Enzymatic Domains |
PDZ 1 271-359 PROSITE-ProRule
PDZ 2 461-546 PROSITE-ProRule
PDZ 3 590-677 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MARK2 | PARD3 | Ser873 | VDDQKAGsPSRDVGP | phosphorylation up-regulates | 22883624 | SIGNOR-198742 |
| AURKA | PARD3 | Ser962 | SSRSGREsVSTASDQ | phosphorylation up-regulates | 19812038 | SIGNOR-188398 |
| PRKCZ | PARD3 | Ser827 | REGFGRQsMSEKRTK | phosphorylation up-regulates | 12390250 | SIGNOR-94523 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MARK2 | phosphorylation up-regulates → | PARD3 PSer873 | phosphorylation up-regulates → | PARD3 | 22883624 | SIGNOR-198742 |
| AURKA | phosphorylation up-regulates → | PARD3 PSer962 | phosphorylation up-regulates → | PARD3 | 19812038 | SIGNOR-188398 |
| PRKCZ | phosphorylation up-regulates → | PARD3 PSer827 | phosphorylation up-regulates → | PARD3 | 12390250 | SIGNOR-94523 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MARK2 | phosphorylation → up-regulates | PARD3 | SIGNOR-198742 |
| AURKA | phosphorylation → up-regulates | PARD3 | SIGNOR-188398 |
| PRKCZ | phosphorylation → up-regulates | PARD3 | SIGNOR-94523 |