Entity Details

Name DGCR8
ID Q8WYQ5
Role substrate
Enzymatic Domains
WW 301-334
PROSITE-ProRule
DRBM 1 511-578
PROSITE-ProRule
DRBM 2 620-685
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ABL1DGCR8Tyr267KRRTEEKyGGDSDHPphosphorylation
up-regulates activity		26126715SIGNOR-262604
ATMDGCR8Ser677RVGKQLAsQKILQLLphosphorylation
up-regulates quantity by stabilization		34188037SIGNOR-277307
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ABL1phosphorylation
up-regulates
→
DGCR8
PTyr267		phosphorylation
up-regulates
→		DGCR826126715SIGNOR-262604
ATMphosphorylation
up-regulates
→
DGCR8
PSer677		phosphorylation
up-regulates
→		DGCR834188037SIGNOR-277307
Regulator Mechanism/Effect Target SIGNOR-ID
ABL1phosphorylation
→
up-regulates activity 		DGCR8SIGNOR-262604
ATMphosphorylation
→
up-regulates quantity by stabilization 		DGCR8SIGNOR-277307