Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CHUK	CREBBP	Ser1382	MKSRFVDsGEMSESF	phosphorylation up-regulates	17434128	SIGNOR-154329
CHUK	CREBBP	Ser1386	FVDSGEMsESFPYRT	phosphorylation up-regulates	17434128	SIGNOR-154333
HIPK2	CREBBP	–		phosphorylation up-regulates activity	26247811	SIGNOR-279191
NLK	CREBBP	–		phosphorylation up-regulates activity	14720327	SIGNOR-280048
PRKCD	CREBBP	Ser437	CLPLKNAsDKRNQQT	phosphorylation unknown	11463380	SIGNOR-249104
PRKCA	CREBBP	–		phosphorylation down-regulates	20577053	SIGNOR-166368
CAMK4	CREBBP	Ser302	PQLASKQsMVNSLPT	phosphorylation up-regulates activity	11970865	SIGNOR-250710

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CHUK	phosphorylation up-regulates →	CREBBP PSer1382	phosphorylation up-regulates →	CREBBP	17434128	SIGNOR-154329
CHUK	phosphorylation up-regulates →	CREBBP PSer1386	phosphorylation up-regulates →	CREBBP	17434128	SIGNOR-154333
PRKCD	phosphorylation up-regulates →	CREBBP PSer437	phosphorylation down-regulates ⊣	CREBBP	11463380	SIGNOR-249104
CAMK4	phosphorylation up-regulates →	CREBBP PSer302	phosphorylation up-regulates →	CREBBP	11970865	SIGNOR-250710

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CHUK	phosphorylation → up-regulates	CREBBP	SIGNOR-154329
CHUK	phosphorylation → up-regulates	CREBBP	SIGNOR-154333
HIPK2	phosphorylation → up-regulates activity	CREBBP	SIGNOR-279191
NLK	phosphorylation → up-regulates activity	CREBBP	SIGNOR-280048
PRKCD	phosphorylation → unknown	CREBBP	SIGNOR-249104
PRKCA	phosphorylation down-regulates	CREBBP	SIGNOR-166368
CAMK4	phosphorylation → up-regulates activity	CREBBP	SIGNOR-250710