Entity Details

Name CyclinB/CDK1_Ser960
ID Q92974
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AURKBARHGEF2Ser960SRLSPPHsPRDFTRMphosphorylation
down-regulates activity		17488622SIGNOR-276062
MARK2ARHGEF2Ser960SRLSPPHsPRDFTRMphosphorylation
down-regulates		22072711SIGNOR-177100
CyclinB/CDK1ARHGEF2Ser960SRLSPPHsPRDFTRMphosphorylation
down-regulates activity		17488622SIGNOR-276060
AURKAARHGEF2Ser960SRLSPPHsPRDFTRMphosphorylation
down-regulates activity		17488622SIGNOR-276061
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AURKBphosphorylation
up-regulates
→
ARHGEF2
PSer960		phosphorylation
down-regulates
⊣		ARHGEF217488622SIGNOR-276062
MARK2phosphorylation
up-regulates
→
ARHGEF2
PSer960		phosphorylation
down-regulates
⊣		ARHGEF222072711SIGNOR-177100
CyclinB/CDK1phosphorylation
up-regulates
→
ARHGEF2
PSer960		phosphorylation
down-regulates
⊣		ARHGEF217488622SIGNOR-276060
AURKAphosphorylation
up-regulates
→
ARHGEF2
PSer960		phosphorylation
down-regulates
⊣		ARHGEF217488622SIGNOR-276061
Regulator Mechanism/Effect Target SIGNOR-ID
AURKBphosphorylation
→
down-regulates activity 		ARHGEF2SIGNOR-276062
MARK2phosphorylation
img/direct_inhibition.png
down-regulates 		ARHGEF2SIGNOR-177100
CyclinB/CDK1phosphorylation
→
down-regulates activity 		ARHGEF2SIGNOR-276060
AURKAphosphorylation
→
down-regulates activity 		ARHGEF2SIGNOR-276061