Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MAPK1	MRTFA	Ser454 View in OncoXplorer	TGSTPPVsPTPSERS	phosphorylation down-regulates	18694962	SIGNOR-179959
MAPK3	MRTFA	Ser454 View in OncoXplorer	TGSTPPVsPTPSERS	phosphorylation down-regulates	18694962	SIGNOR-179963
ERK1/2	MRTFA	–		phosphorylation down-regulates	18694962	SIGNOR-270131
PKN1	MRTFA	–		phosphorylation down-regulates activity	31564129	SIGNOR-280067
Gbeta	MRTFA	–		phosphorylation down-regulates	18694962	SIGNOR-269996
MAPK3	MRTFA	Ser454 View in OncoXplorer	TGSTPPVsPTPSERS	phosphorylation down-regulates	22139079	SIGNOR-195157
MAPK1	MRTFA	Ser454 View in OncoXplorer	TGSTPPVsPTPSERS	phosphorylation down-regulates	22139079	SIGNOR-195153

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MAPK1	phosphorylation up-regulates →	MRTFA PSer454	phosphorylation down-regulates ⊣	MRTFA	18694962	SIGNOR-179959
MAPK3	phosphorylation up-regulates →	MRTFA PSer454	phosphorylation down-regulates ⊣	MRTFA	18694962	SIGNOR-179963
MAPK3	phosphorylation up-regulates →	MRTFA PSer454	phosphorylation down-regulates ⊣	MRTFA	22139079	SIGNOR-195157
MAPK1	phosphorylation up-regulates →	MRTFA PSer454	phosphorylation down-regulates ⊣	MRTFA	22139079	SIGNOR-195153

Regulator	Mechanism/Effect	Target	SIGNOR-ID
MAPK1	phosphorylation down-regulates	MRTFA	SIGNOR-179959
MAPK3	phosphorylation down-regulates	MRTFA	SIGNOR-179963
ERK1/2	phosphorylation down-regulates	MRTFA	SIGNOR-270131
PKN1	phosphorylation → down-regulates activity	MRTFA	SIGNOR-280067
Gbeta	phosphorylation down-regulates	MRTFA	SIGNOR-269996
MAPK3	phosphorylation down-regulates	MRTFA	SIGNOR-195157
MAPK1	phosphorylation down-regulates	MRTFA	SIGNOR-195153