| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | MRTFA | Ser454 | TGSTPPVsPTPSERS | phosphorylation down-regulates | 18694962 | SIGNOR-179963 |
| MAPK3 | MRTFA | Ser454 | TGSTPPVsPTPSERS | phosphorylation down-regulates | 22139079 | SIGNOR-195157 |
| MAPK1 | MRTFA | Ser454 | TGSTPPVsPTPSERS | phosphorylation down-regulates | 22139079 | SIGNOR-195153 |
| MAPK1 | MRTFA | Ser454 | TGSTPPVsPTPSERS | phosphorylation down-regulates | 18694962 | SIGNOR-179959 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | phosphorylation up-regulates → | MRTFA PSer454 | phosphorylation down-regulates ⊣ | MRTFA | 18694962 | SIGNOR-179963 |
| MAPK3 | phosphorylation up-regulates → | MRTFA PSer454 | phosphorylation down-regulates ⊣ | MRTFA | 22139079 | SIGNOR-195157 |
| MAPK1 | phosphorylation up-regulates → | MRTFA PSer454 | phosphorylation down-regulates ⊣ | MRTFA | 22139079 | SIGNOR-195153 |
| MAPK1 | phosphorylation up-regulates → | MRTFA PSer454 | phosphorylation down-regulates ⊣ | MRTFA | 18694962 | SIGNOR-179959 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK3 | phosphorylation down-regulates | MRTFA | SIGNOR-179963 |
| MAPK3 | phosphorylation down-regulates | MRTFA | SIGNOR-195157 |
| MAPK1 | phosphorylation down-regulates | MRTFA | SIGNOR-195153 |
| MAPK1 | phosphorylation down-regulates | MRTFA | SIGNOR-179959 |
