| Name | FERMT2 |
| ID | Q96AC1 |
| Role | substrate |
| Enzymatic Domains |
FERM 189-661
PH 380-476 PROSITE-ProRule |
View in ![]() |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | FERMT2 | Ser175 | GPLITPGsGSIYSSP | phosphorylation down-regulates quantity by destabilization | 35469017 | SIGNOR-276716 |
| SRC | FERMT2 | Tyr193 | SKTMTPTyDAHDGSP | phosphorylation up-regulates activity | 26037143 | SIGNOR-266100 |
| CyclinB/CDK1 | FERMT2 | Ser177 | LITPGSGsIYSSPGL | phosphorylation down-regulates quantity by destabilization | 35469017 | SIGNOR-276713 |
| CyclinB/CDK1 | FERMT2 | Ser186 | YSSPGLYsKTMTPTY | phosphorylation down-regulates quantity by destabilization | 35469017 | SIGNOR-276714 |
| CyclinB/CDK1 | FERMT2 | Ser180 | PGSGSIYsSPGLYSK | phosphorylation down-regulates quantity by destabilization | 35469017 | SIGNOR-276715 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | phosphorylation up-regulates → | FERMT2 PSer175 | phosphorylation down-regulates ⊣ | FERMT2 | 35469017 | SIGNOR-276716 |
| SRC | phosphorylation up-regulates → | FERMT2 PTyr193 | phosphorylation up-regulates → | FERMT2 | 26037143 | SIGNOR-266100 |
| CyclinB/CDK1 | phosphorylation up-regulates → | FERMT2 PSer177 | phosphorylation down-regulates ⊣ | FERMT2 | 35469017 | SIGNOR-276713 |
| CyclinB/CDK1 | phosphorylation up-regulates → | FERMT2 PSer186 | phosphorylation down-regulates ⊣ | FERMT2 | 35469017 | SIGNOR-276714 |
| CyclinB/CDK1 | phosphorylation up-regulates → | FERMT2 PSer180 | phosphorylation down-regulates ⊣ | FERMT2 | 35469017 | SIGNOR-276715 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinB/CDK1 | phosphorylation![]() down-regulates quantity by destabilization | FERMT2 | SIGNOR-276716 |
| SRC | phosphorylation → up-regulates activity | FERMT2 | SIGNOR-266100 |
| CyclinB/CDK1 | phosphorylation![]() down-regulates quantity by destabilization | FERMT2 | SIGNOR-276713 |
| CyclinB/CDK1 | phosphorylation![]() down-regulates quantity by destabilization | FERMT2 | SIGNOR-276714 |
| CyclinB/CDK1 | phosphorylation![]() down-regulates quantity by destabilization | FERMT2 | SIGNOR-276715 |