Entity Details

Name MAPK8_Thr530
ID Q96EB6
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK8SIRT1Thr530YLSELPPtPLHVSEDphosphorylation
up-regulates		20027304SIGNOR-162322
DYRK1ASIRT1Thr530YLSELPPtPLHVSEDphosphorylation
up-regulates activity		20167603SIGNOR-278473
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK8phosphorylation
up-regulates
→
SIRT1
PThr530		phosphorylation
up-regulates
→		SIRT120027304SIGNOR-162322
DYRK1Aphosphorylation
up-regulates
→
SIRT1
PThr530		phosphorylation
up-regulates
→		SIRT120167603SIGNOR-278473
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK8phosphorylation
→
up-regulates 		SIRT1SIGNOR-162322
DYRK1Aphosphorylation
→
up-regulates activity 		SIRT1SIGNOR-278473