| Name | PELI1 |
| ID | Q96FA3 |
| Role | substrate |
| Enzymatic Domains |
FHA; atypical 13-200 UniProtKB |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| IRAK4 | PELI1 | Ser76 | ISNKDQHsISYTLSR | phosphorylation up-regulates activity | 19264966 | SIGNOR-276127 |
| IRAK4 | PELI1 | Thr86 | YTLSRAQtVVVEYTH | phosphorylation up-regulates activity | 19264966 | SIGNOR-276128 |
| IRAK1 | PELI1 | Thr288 | QCPVGFNtLAFPSMK | phosphorylation up-regulates activity | 19264966 | SIGNOR-276136 |
| IRAK4 | PELI1 | Ser78 | NKDQHSIsYTLSRAQ | phosphorylation up-regulates activity | 19264966 | SIGNOR-276126 |
| IRAK1 | PELI1 | Thr288 | QCPVGFNtLAFPSMK | phosphorylation up-regulates activity | 12496252 | SIGNOR-96751 |
| IRAK1 | PELI1 | Ser82 | HSISYTLsRAQTVVV | phosphorylation up-regulates activity | 19264966 | SIGNOR-276139 |
| IRAK1 | PELI1 | Thr86 | YTLSRAQtVVVEYTH | phosphorylation up-regulates activity | 12496252 | SIGNOR-96759 |
| IRAK1 | PELI1 | Ser76 | ISNKDQHsISYTLSR | phosphorylation up-regulates activity | 19264966 | SIGNOR-276134 |
| IRAK1 | PELI1 | Thr86 | YTLSRAQtVVVEYTH | phosphorylation up-regulates activity | 19264966 | SIGNOR-276135 |
| IRAK4 | PELI1 | Ser293 | FNTLAFPsMKRKDVV | phosphorylation up-regulates activity | 19264966 | SIGNOR-276130 |
| EGFR | PELI1 | Tyr154 | PPFTARIyAAGFDSS | phosphorylation up-regulates activity | 36841821 | SIGNOR-277873 |
| IRAK1 | PELI1 | Ser293 | FNTLAFPsMKRKDVV | phosphorylation up-regulates activity | 19264966 | SIGNOR-276137 |
| IRAK1 | PELI1 | Ser78 | NKDQHSIsYTLSRAQ | phosphorylation up-regulates activity | 19264966 | SIGNOR-276133 |
| IRAK4 | PELI1 | Thr288 | QCPVGFNtLAFPSMK | phosphorylation up-regulates activity | 19264966 | SIGNOR-276129 |
| IRAK1 | PELI1 | Ser82 | HSISYTLsRAQTVVV | phosphorylation up-regulates activity | 12496252 | SIGNOR-96747 |
| IRAK1 | PELI1 | Thr80 | DQHSISYtLSRAQTV | phosphorylation up-regulates activity | 19264966 | SIGNOR-276138 |
| IRAK4 | PELI1 | Ser82 | HSISYTLsRAQTVVV | phosphorylation up-regulates activity | 19264966 | SIGNOR-276132 |
| IRAK1 | PELI1 | Ser78 | NKDQHSIsYTLSRAQ | phosphorylation up-regulates activity | 12496252 | SIGNOR-96743 |
| DAPK1 | PELI1 | Ser39 | GDRGRRKsRFALFKR | phosphorylation down-regulates quantity by destabilization | 33052227 | SIGNOR-277531 |
| IRAK1 | PELI1 | Ser76 | ISNKDQHsISYTLSR | phosphorylation up-regulates activity | 12496252 | SIGNOR-96739 |
| IRAK1 | PELI1 | Ser293 | FNTLAFPsMKRKDVV | phosphorylation up-regulates activity | 12496252 | SIGNOR-96735 |
| EGFR | PELI1 | Thr264 | EGLSHTPtVKHLEAL | phosphorylation up-regulates activity | 36841821 | SIGNOR-277874 |
| IRAK4 | PELI1 | Thr80 | DQHSISYtLSRAQTV | phosphorylation up-regulates activity | 19264966 | SIGNOR-276131 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| IRAK4 | phosphorylation up-regulates → | PELI1 PSer76 | phosphorylation up-regulates → | PELI1 | 19264966 | SIGNOR-276127 |
| IRAK4 | phosphorylation up-regulates → | PELI1 PThr86 | phosphorylation up-regulates → | PELI1 | 19264966 | SIGNOR-276128 |
| IRAK1 | phosphorylation up-regulates → | PELI1 PThr288 | phosphorylation up-regulates → | PELI1 | 19264966 | SIGNOR-276136 |
| IRAK4 | phosphorylation up-regulates → | PELI1 PSer78 | phosphorylation up-regulates → | PELI1 | 19264966 | SIGNOR-276126 |
| IRAK1 | phosphorylation up-regulates → | PELI1 PThr288 | phosphorylation up-regulates → | PELI1 | 12496252 | SIGNOR-96751 |
| IRAK1 | phosphorylation up-regulates → | PELI1 PSer82 | phosphorylation up-regulates → | PELI1 | 19264966 | SIGNOR-276139 |
| IRAK1 | phosphorylation up-regulates → | PELI1 PThr86 | phosphorylation up-regulates → | PELI1 | 12496252 | SIGNOR-96759 |
| IRAK1 | phosphorylation up-regulates → | PELI1 PSer76 | phosphorylation up-regulates → | PELI1 | 19264966 | SIGNOR-276134 |
| IRAK1 | phosphorylation up-regulates → | PELI1 PThr86 | phosphorylation up-regulates → | PELI1 | 19264966 | SIGNOR-276135 |
| IRAK4 | phosphorylation up-regulates → | PELI1 PSer293 | phosphorylation up-regulates → | PELI1 | 19264966 | SIGNOR-276130 |
| EGFR | phosphorylation up-regulates → | PELI1 PTyr154 | phosphorylation up-regulates → | PELI1 | 36841821 | SIGNOR-277873 |
| IRAK1 | phosphorylation up-regulates → | PELI1 PSer293 | phosphorylation up-regulates → | PELI1 | 19264966 | SIGNOR-276137 |
| IRAK1 | phosphorylation up-regulates → | PELI1 PSer78 | phosphorylation up-regulates → | PELI1 | 19264966 | SIGNOR-276133 |
| IRAK4 | phosphorylation up-regulates → | PELI1 PThr288 | phosphorylation up-regulates → | PELI1 | 19264966 | SIGNOR-276129 |
| IRAK1 | phosphorylation up-regulates → | PELI1 PSer82 | phosphorylation up-regulates → | PELI1 | 12496252 | SIGNOR-96747 |
| IRAK1 | phosphorylation up-regulates → | PELI1 PThr80 | phosphorylation up-regulates → | PELI1 | 19264966 | SIGNOR-276138 |
| IRAK4 | phosphorylation up-regulates → | PELI1 PSer82 | phosphorylation up-regulates → | PELI1 | 19264966 | SIGNOR-276132 |
| IRAK1 | phosphorylation up-regulates → | PELI1 PSer78 | phosphorylation up-regulates → | PELI1 | 12496252 | SIGNOR-96743 |
| DAPK1 | phosphorylation up-regulates → | PELI1 PSer39 | phosphorylation down-regulates ⊣ | PELI1 | 33052227 | SIGNOR-277531 |
| IRAK1 | phosphorylation up-regulates → | PELI1 PSer76 | phosphorylation up-regulates → | PELI1 | 12496252 | SIGNOR-96739 |
| IRAK1 | phosphorylation up-regulates → | PELI1 PSer293 | phosphorylation up-regulates → | PELI1 | 12496252 | SIGNOR-96735 |
| EGFR | phosphorylation up-regulates → | PELI1 PThr264 | phosphorylation up-regulates → | PELI1 | 36841821 | SIGNOR-277874 |
| IRAK4 | phosphorylation up-regulates → | PELI1 PThr80 | phosphorylation up-regulates → | PELI1 | 19264966 | SIGNOR-276131 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| IRAK4 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-276127 |
| IRAK4 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-276128 |
| IRAK1 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-276136 |
| IRAK4 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-276126 |
| IRAK1 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-96751 |
| IRAK1 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-276139 |
| IRAK1 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-96759 |
| IRAK1 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-276134 |
| IRAK1 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-276135 |
| IRAK4 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-276130 |
| EGFR | phosphorylation → up-regulates activity | PELI1 | SIGNOR-277873 |
| IRAK1 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-276137 |
| IRAK1 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-276133 |
| IRAK4 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-276129 |
| IRAK1 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-96747 |
| IRAK1 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-276138 |
| IRAK4 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-276132 |
| IRAK1 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-96743 |
| DAPK1 | phosphorylation down-regulates quantity by destabilization | PELI1 | SIGNOR-277531 |
| IRAK1 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-96739 |
| IRAK1 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-96735 |
| EGFR | phosphorylation → up-regulates activity | PELI1 | SIGNOR-277874 |
| IRAK4 | phosphorylation → up-regulates activity | PELI1 | SIGNOR-276131 |