Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CAMKK2	PRKAA2	Thr172	SDGEFLRtSCGSPNY	phosphorylation up-regulates	15980064	SIGNOR-138364
CAMKK2	PRKAA2	Thr172	SDGEFLRtSCGSPNY	phosphorylation up-regulates	19958286	SIGNOR-161929
CAMKK2	PRKAA1	Thr183	SDGEFLRtSCGSPNY	phosphorylation up-regulates	21918180	SIGNOR-176602
CAMKK2	CAMK1	Thr177	DPGSVLStACGTPGY	phosphorylation up-regulates activity	7641687	SIGNOR-250716
CAMKK2	CAMK4	Thr200	EHQVLMKtVCGTPGY	phosphorylation up-regulates activity	7615569	SIGNOR-250718
CAMKK2	CAMKK2	Thr483	KHIPSLAtVILVKTM	phosphorylation up-regulates	22778263	SIGNOR-198107
CAMKK2	AMPK	–		phosphorylation up-regulates	15980064	SIGNOR-217496

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CAMKK2	phosphorylation up-regulates →	PRKAA2 PThr172	phosphorylation up-regulates →	PRKAA2	15980064	SIGNOR-138364
CAMKK2	phosphorylation up-regulates →	PRKAA2 PThr172	phosphorylation up-regulates →	PRKAA2	19958286	SIGNOR-161929
CAMKK2	phosphorylation up-regulates →	PRKAA1 PThr183	phosphorylation up-regulates →	PRKAA1	21918180	SIGNOR-176602
CAMKK2	phosphorylation up-regulates →	CAMK1 PThr177	phosphorylation up-regulates →	CAMK1	7641687	SIGNOR-250716
CAMKK2	phosphorylation up-regulates →	CAMK4 PThr200	phosphorylation up-regulates →	CAMK4	7615569	SIGNOR-250718
CAMKK2	phosphorylation up-regulates →	CAMKK2 PThr483	phosphorylation up-regulates →	CAMKK2	22778263	SIGNOR-198107

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CAMKK2	phosphorylation → up-regulates	PRKAA2	SIGNOR-138364
CAMKK2	phosphorylation → up-regulates	PRKAA2	SIGNOR-161929
CAMKK2	phosphorylation → up-regulates	PRKAA1	SIGNOR-176602
CAMKK2	phosphorylation → up-regulates activity	CAMK1	SIGNOR-250716
CAMKK2	phosphorylation → up-regulates activity	CAMK4	SIGNOR-250718
CAMKK2	phosphorylation → up-regulates	CAMKK2	SIGNOR-198107
CAMKK2	phosphorylation → up-regulates	AMPK	SIGNOR-217496