| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PKA | CAMKK2 | Ser511 | RREERSLsAPGNLLT | phosphorylation down-regulates activity | 32913128 | SIGNOR-277240 |
| DAPK1 | CAMKK2 | Ser511 | RREERSLsAPGNLLT | phosphorylation down-regulates | 15209507 | SIGNOR-126241 |
| PKA | CAMKK2 | Ser511 | RREERSLsAPGNLLT | phosphorylation down-regulates | 22778263 | SIGNOR-198154 |
| DAPK1 | CAMKK2 | Ser511 | RREERSLsAPGNLLT | phosphorylation unknown | 15209507 | SIGNOR-126245 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PKA | phosphorylation up-regulates → | CAMKK2 PSer511 | phosphorylation down-regulates ⊣ | CAMKK2 | 32913128 | SIGNOR-277240 |
| DAPK1 | phosphorylation up-regulates → | CAMKK2 PSer511 | phosphorylation down-regulates ⊣ | CAMKK2 | 15209507 | SIGNOR-126241 |
| PKA | phosphorylation up-regulates → | CAMKK2 PSer511 | phosphorylation down-regulates ⊣ | CAMKK2 | 22778263 | SIGNOR-198154 |
| DAPK1 | phosphorylation up-regulates → | CAMKK2 PSer511 | phosphorylation down-regulates ⊣ | CAMKK2 | 15209507 | SIGNOR-126245 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PKA | phosphorylation → down-regulates activity | CAMKK2 | SIGNOR-277240 |
| DAPK1 | phosphorylation down-regulates | CAMKK2 | SIGNOR-126241 |
| PKA | phosphorylation down-regulates | CAMKK2 | SIGNOR-198154 |
| DAPK1 | phosphorylation → unknown | CAMKK2 | SIGNOR-126245 |
