| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3A | CAMKK2 | Ser137 | PVSSPQSsPRLPRRP | phosphorylation down-regulates | 22778263 | SIGNOR-198130 |
| CDK5 | CAMKK2 | Ser137 | PVSSPQSsPRLPRRP | phosphorylation down-regulates | 22778263 | SIGNOR-197945 |
| GSK3B | CAMKK2 | Ser137 | PVSSPQSsPRLPRRP | phosphorylation down-regulates | 22778263 | SIGNOR-198142 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3A | phosphorylation up-regulates → | CAMKK2 PSer137 | phosphorylation down-regulates ⊣ | CAMKK2 | 22778263 | SIGNOR-198130 |
| CDK5 | phosphorylation up-regulates → | CAMKK2 PSer137 | phosphorylation down-regulates ⊣ | CAMKK2 | 22778263 | SIGNOR-197945 |
| GSK3B | phosphorylation up-regulates → | CAMKK2 PSer137 | phosphorylation down-regulates ⊣ | CAMKK2 | 22778263 | SIGNOR-198142 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3A | phosphorylation down-regulates | CAMKK2 | SIGNOR-198130 |
| CDK5 | phosphorylation down-regulates | CAMKK2 | SIGNOR-197945 |
| GSK3B | phosphorylation down-regulates | CAMKK2 | SIGNOR-198142 |
