| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK1 | SPEN | Ser3486 | QPAPKQDsSPHLTSQ | phosphorylation down-regulates activity | 15824732 | SIGNOR-278968 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK1 | phosphorylation up-regulates → | SPEN PSer3486 | phosphorylation down-regulates ⊣ | SPEN | 15824732 | SIGNOR-278968 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PAK1 | phosphorylation → down-regulates activity | SPEN | SIGNOR-278968 |
