| + |
SPEN | down-regulates 
binding
|
RBPJ |
0.69 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-94201 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 12374742 |
We identified sharp as an rbp-jkappa/cbf-1-interacting corepressor in a yeast two-hybrid screen. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MSX2 | up-regulates 
binding
|
SPEN |
0.497 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-188572 |
|
|
Homo sapiens |
T-lymphocyte, Leukemia Cell, JURKAT Cell |
| pmid |
sentence |
| 19835636 |
Furthermore, in addition to msx2, both tlx1 and nkx2-5 proteins interacted with notch-pathway repressors, spen/mint/sharp and tle1/grg1, representing a potential mechanism for (de)regulation. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NCOR2 | up-regulates
binding
|
SPEN |
0.483 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-107260 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11331609 |
Sharp is a potent transcriptional repressor whose repression domain (rd) interacts directly with smrt |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RBBP8 | down-regulates
binding
|
SPEN |
0.516 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-141616 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16287852 |
We identify the ctip and ctbp corepressors as novel components of the human rbp-jk/sharp-corepressor complex and show that ctip binds directly to the sharp repression domain. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
SPEN
- 
- 