| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK1 | KIF2C | Ser111 | KESLRSRsTRMSTVS | phosphorylation down-regulates | 23055517 | SIGNOR-199080 |
| AURKB | KIF2C | Ser111 | KESLRSRsTRMSTVS | phosphorylation down-regulates | 17567953 | SIGNOR-155894 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK1 | phosphorylation up-regulates → | KIF2C PSer111 | phosphorylation down-regulates ⊣ | KIF2C | 23055517 | SIGNOR-199080 |
| AURKB | phosphorylation up-regulates → | KIF2C PSer111 | phosphorylation down-regulates ⊣ | KIF2C | 17567953 | SIGNOR-155894 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PAK1 | phosphorylation![]() down-regulates | KIF2C | SIGNOR-199080 |
| AURKB | phosphorylation![]() down-regulates | KIF2C | SIGNOR-155894 |