Entity Details

Name MAP3K5_Thr838
ID Q99683
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAP3K6MAP3K5Thr838GINPCTEtFTGTLQYphosphorylation
up-regulates quantity by stabilization		17210579SIGNOR-260832
MAP3K5MAP3K5Thr838GINPCTEtFTGTLQYphosphorylation
up-regulates activity		17937911SIGNOR-158427
MAP3K6MAP3K5Thr838GINPCTEtFTGTLQYphosphorylation
up-regulates activity		17210579SIGNOR-260773
PGAM5MAP3K5Thr838GINPCTEtFTGTLQYdephosphorylation
up-regulates activity		19590015SIGNOR-277984
PPM1LMAP3K5Thr838GINPCTEtFTGTLQYdephosphorylation
down-regulates		17456047SIGNOR-154554
PPP5CMAP3K5Thr838GINPCTEtFTGTLQYdephosphorylation
down-regulates activity		11689443SIGNOR-111301
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAP3K6phosphorylation
up-regulates
→
MAP3K5
PThr838		phosphorylation
up-regulates
→		MAP3K517210579SIGNOR-260832
MAP3K5phosphorylation
up-regulates
→
MAP3K5
PThr838		phosphorylation
up-regulates
→		MAP3K517937911SIGNOR-158427
MAP3K6phosphorylation
up-regulates
→
MAP3K5
PThr838		phosphorylation
up-regulates
→		MAP3K517210579SIGNOR-260773
PGAM5dephosphorylation
down-regulates
⊣
MAP3K5
PThr838		dephosphorylation
down-regulates
⊣		MAP3K519590015SIGNOR-277984
PPM1Ldephosphorylation
down-regulates
⊣
MAP3K5
PThr838		dephosphorylation
up-regulates
→		MAP3K517456047SIGNOR-154554
PPP5Cdephosphorylation
down-regulates
⊣
MAP3K5
PThr838		dephosphorylation
up-regulates
→		MAP3K511689443SIGNOR-111301
Regulator Mechanism/Effect Target SIGNOR-ID
MAP3K6phosphorylation
→
up-regulates quantity by stabilization 		MAP3K5SIGNOR-260832
MAP3K5phosphorylation
→
up-regulates activity 		MAP3K5SIGNOR-158427
MAP3K6phosphorylation
→
up-regulates activity 		MAP3K5SIGNOR-260773
PGAM5dephosphorylation
→
up-regulates activity 		MAP3K5SIGNOR-277984
PPM1Ldephosphorylation
img/direct_inhibition.png
down-regulates 		MAP3K5SIGNOR-154554
PPP5Cdephosphorylation
→
down-regulates activity 		MAP3K5SIGNOR-111301