| Name | IFIH1 |
| ID | Q9BYX4 |
| Role | substrate |
| Enzymatic Domains |
CARD 1 7-97
CARD 2 110-190
Helicase ATP-binding 316-509 PROSITE-ProRule
Helicase C-terminal 700-882 PROSITE-ProRule
RLR CTR 893-1020 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP1CA | IFIH1 | Ser88 | EALRRTGsPLAARYM | dephosphorylation up-regulates activity | 23499489 | SIGNOR-264577 |
| PPP1CC | IFIH1 | Ser88 | EALRRTGsPLAARYM | dephosphorylation up-regulates activity | 25865883 | SIGNOR-264578 |
| PPP1CC | IFIH1 | Ser88 | EALRRTGsPLAARYM | dephosphorylation up-regulates activity | 23499489 | SIGNOR-264579 |
| RIOK3 | IFIH1 | Ser828 | GRARADEsTYVLVAH | phosphorylation down-regulates activity | 25865883 | SIGNOR-264576 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP1CA | dephosphorylation down-regulates ⊣ | IFIH1 PSer88 | dephosphorylation down-regulates ⊣ | IFIH1 | 23499489 | SIGNOR-264577 |
| PPP1CC | dephosphorylation down-regulates ⊣ | IFIH1 PSer88 | dephosphorylation down-regulates ⊣ | IFIH1 | 25865883 | SIGNOR-264578 |
| PPP1CC | dephosphorylation down-regulates ⊣ | IFIH1 PSer88 | dephosphorylation down-regulates ⊣ | IFIH1 | 23499489 | SIGNOR-264579 |
| RIOK3 | phosphorylation up-regulates → | IFIH1 PSer828 | phosphorylation down-regulates ⊣ | IFIH1 | 25865883 | SIGNOR-264576 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP1CA | dephosphorylation → up-regulates activity | IFIH1 | SIGNOR-264577 |
| PPP1CC | dephosphorylation → up-regulates activity | IFIH1 | SIGNOR-264578 |
| PPP1CC | dephosphorylation → up-regulates activity | IFIH1 | SIGNOR-264579 |
| RIOK3 | phosphorylation → down-regulates activity | IFIH1 | SIGNOR-264576 |