| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP1CA | IFIH1 | Ser88 | EALRRTGsPLAARYM | dephosphorylation up-regulates activity | 23499489 | SIGNOR-264577 |
| PPP1CC | IFIH1 | Ser88 | EALRRTGsPLAARYM | dephosphorylation up-regulates activity | 25865883 | SIGNOR-264578 |
| PPP1CC | IFIH1 | Ser88 | EALRRTGsPLAARYM | dephosphorylation up-regulates activity | 23499489 | SIGNOR-264579 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP1CA | dephosphorylation down-regulates ⊣ | IFIH1 PSer88 | dephosphorylation down-regulates ⊣ | IFIH1 | 23499489 | SIGNOR-264577 |
| PPP1CC | dephosphorylation down-regulates ⊣ | IFIH1 PSer88 | dephosphorylation down-regulates ⊣ | IFIH1 | 25865883 | SIGNOR-264578 |
| PPP1CC | dephosphorylation down-regulates ⊣ | IFIH1 PSer88 | dephosphorylation down-regulates ⊣ | IFIH1 | 23499489 | SIGNOR-264579 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP1CA | dephosphorylation → up-regulates activity | IFIH1 | SIGNOR-264577 |
| PPP1CC | dephosphorylation → up-regulates activity | IFIH1 | SIGNOR-264578 |
| PPP1CC | dephosphorylation → up-regulates activity | IFIH1 | SIGNOR-264579 |
